Milipore Filter Capsule Opticap XL 5 Polygard-CR 5 um - 1.5" Sanitary Fittings

Millipore KR05A05TT1 Opticap® XL 5 Capsule Filter (Polygard® CR, 5.0 µm)

The Millipore KR05A05TT1 is a high-capacity, disposable capsule filter engineered for effective particle removal and prefiltration in biopharmaceutical and industrial processes. Featuring Polygard® CR media—a graded-density polypropylene depth matrix—this filter provides exceptional dirt-holding capacity and broad chemical compatibility. The 5.0 µm nominal pore size is ideal for the clarification of cell culture media, buffers, and specialty chemicals, protecting expensive downstream sterilizing-grade membranes from premature fouling. The self-contained Opticap® XL 5 design eliminates the need for stainless steel housings, reducing setup time, cleaning validation costs, and the risk of cross-contamination.

Technical Performance and Design

• Graded-Density Depth Media: The Polygard® CR media utilizes a multi-layered polypropylene structure that traps larger particles in the outer layers and finer particles deeper within, maximizing throughput and service life.

• All-Polypropylene Construction: Both the media and the rugged housing are made of virgin polypropylene, ensuring extremely low extractable levels and compatibility with a wide range of acids, bases, and solvents.

• Sanitary Flange Connections (TT1): Features 1-1/2 inch (38 mm) Sanitary Flanges on both the inlet and outlet, providing a secure, leak-proof interface compatible with standard Tri-Clamp fittings used in sterile fluid paths.

• High Stress Resistance: The patented Opticap® XL capsule design is engineered for superior thermal and hydraulic stress resistance, ensuring reliability during vigorous process conditions and pressure spikes.

Product Specifications

• Catalog Number: KR05A05TT1

• Media Type: Polygard® CR (Polypropylene Depth Filter)

• Pore Size: 5.0 µm (Nominal)

• Filtration Area: 0.23 m² (approx. 2.5 ft²)

• Connections (Inlet/Outlet): 1-1/2 inch Sanitary Flange (TC)

• Vent/Drain: 1/4 inch Hose Barb

• Max Operating Pressure: 5.5 bar (80 psi) @ 25 °C; 1.0 bar (15 psi) @ 80 °C

• Sterility/Sanitation: Autoclavable (up to 3 cycles of 30 min @ 126 °C); Not in-line steam sterilizable.

Key Benefits & Applications

• Upstream Clarification: Efficiently removes bulk particulates from cell culture supernatants and fermentation broths prior to downstream purification steps.

• General Buffer Filtration: An excellent choice for the clarification of high-volume buffers and reagents where high flow rates and high dirt-holding capacity are required.

• Process Scalability: The Opticap® XL series allows for easy scale-up from R&D to full-scale production using the same Polygard® media chemistry across different capsule sizes.

• Regulatory Compliance: All component materials meet FDA Indirect Food Additive requirements (21 CFR 177-182) and USP Class VI Biological Tests for Plastics.

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