Millipore Filter Capsule Opticap XL 10 Polygard-CR 5 um KR05A10TT1

Millipore KR05A10TT1 Opticap XL 10 Polygard-CR 5 µm Filter Capsule

The Millipore KR05A10TT1 is a high-capacity, disposable Opticap XL 10 capsule filter engineered for the efficient clarification and pre-filtration of aqueous solutions and process fluids. Featuring 5 µm Polygard-CR depth media, this capsule is constructed from multiple layers of graduated-density polypropylene fleece, providing exceptional dirt-holding capacity and high throughput. The Opticap XL 10 format is designed to handle larger production volumes, minimizing cleaning and validation requirements by offering a convenient, single-use solution. With its robust polypropylene housing and 1.5-inch sanitary flange connections, the KR05A10TT1 ensures a secure, leak-proof interface in high-pressure environments, making it an essential component for protecting sensitive downstream membranes in vaccine, protein, and chemical manufacturing.

Technical Performance and Design

• Polygard-CR Depth Media: The 5 µm nominal pore size media utilizes a graduated density structure to capture a wide range of particulate sizes, ensuring maximum protection for more expensive downstream filters.

• High Filtration Area: With an effective filtration area of approximately 0.38 m², this XL 10 capsule is optimized for handling large fluid volumes with minimal pressure drop.

• All-Polypropylene Construction: The media, support materials, and housing are manufactured from high-purity polypropylene, providing broad chemical compatibility and an exceptionally low extractable profile.

• Sanitary Design: Equipped with 1.5-inch (38 mm) sanitary flange (tri-clamp) inlet and outlet connections to maintain aseptic integrity and ensure compatibility with standard bioprocessing equipment.

Product Specifications

• Catalog Number: KR05A10TT1

• Device Size: Opticap XL 10 (10-inch nominal length)

• Pore Size: 5.0 µm (Nominal)

• Filtration Area: 0.38 m² (4.1 ft²)

• Connections: 1.5 in. (38 mm) Sanitary Flange Inlet / 1.5 in. (38 mm) Sanitary Flange Outlet

• Maximum Operating Pressure: 80 psi (5.5 bar) @ 25°C

• Materials: Polypropylene Media and Housing; Silicone O-rings/Seals.

• Sterilization: Autoclavable (up to 3 cycles at 126°C); not for in-line steam sterilization.

Key Benefits & Applications

• Downstream Protection: The primary choice for pre-filtering cell culture harvests, buffers, and reagents to extend the life of 0.2 µm and 0.1 µm sterilizing-grade filters.

• Low Non-Specific Binding: The pure polypropylene media minimizes the adsorption of valuable proteins and active pharmaceutical ingredients (APIs).

• Biopharmaceutical Clarification: Ideal for the removal of lipids, cell debris, and aggregates in vaccine and monoclonal antibody production.

• Chemical Compatibility: Suitable for filtering a wide range of acids, bases, and solvents used in pharmaceutical compounding and industrial manufacturing.

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