{"product_id":"millipore-filter-capsule-polysep-ii-opticap-xl-5-mce-0-2-um","title":"Millipore Filter Capsule Polysep II Opticap XL 5 MCE 0.2 um","description":"\u003ch3\u003eMillipore KGW3A05HH1 Opticap® XL 5 Polysep™ II 0.2 µm Filter Capsule\u003c\/h3\u003e\n\u003cp\u003eThe Millipore KGW3A05HH1 is a high-capacity, heterogeneous double-layer capsule filter designed for the efficient bioburden reduction and clarification of biopharmaceutical process fluids. Part of the Opticap® XL 5 family, this unit utilizes Polysep™ II media, which combines a 1.0 µm pre-filter with a 0.2 µm final layer, both composed of high-purity Mixed Cellulose Esters (MCE). This unique \"built-in pre-filtration\" design provides significantly higher total throughput and dirt-holding capacity compared to single-layer filters, making it ideal for processing nutrient-rich cell culture media, complex buffers, and biological intermediates. Featuring robust 9\/16\" (14 mm) hose barb connections, this capsule is engineered for seamless integration into flexible tubing manifolds and single-use assemblies.\u003c\/p\u003e\n\n\u003ch3\u003eTechnical Performance and Design\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eHeterogeneous MCE Double-Layer:\u003c\/b\u003e The 1.0\/0.2 µm graduated pore structure effectively captures a wide range of particulate sizes, protecting the final 0.2 µm layer from premature fouling and extending the filter's service life.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eOpticap® XL 5 Thermal Stability:\u003c\/b\u003e Constructed with a high-durability polypropylene housing that can withstand up to 3 autoclave cycles (30 min @ 121 °C), allowing for flexible sterilization options in clinical and research settings.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eEnhanced Flow Dynamics:\u003c\/b\u003e The XL 5 format provides a generous 0.19 m² (2.0 ft²) of effective filtration area, delivering high flux rates and reducing the time required for large-volume batch processing.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eLow-Extractable Construction:\u003c\/b\u003e Manufactured without the use of adhesives or surfactants, ensuring an exceptionally clean filtrate with minimal interference in sensitive protein purification or analytical assays.\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eProduct Specifications\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eCatalog Number:\u003c\/b\u003e KGW3A05HH1\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eMedia Type:\u003c\/b\u003e Polysep™ II (Mixed Cellulose Esters \/ MCE)\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003ePore Size:\u003c\/b\u003e 1.0 µm (Pre-filter) \/ 0.2 µm (Final-filter)\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eFormat:\u003c\/b\u003e Opticap® XL 5 Capsule (5-inch nominal length)\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eInlet\/Outlet:\u003c\/b\u003e 9\/16 inch (14 mm) Hose Barb\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eFiltration Area:\u003c\/b\u003e 0.19 m² (2.0 ft²)\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eMax Pressure:\u003c\/b\u003e 5.5 bar (80 psi) @ 23 °C; 1.0 bar (15 psi) @ 80 °C\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003ePurity:\u003c\/b\u003e Certified Non-pyrogenic (≤0.5 EU\/mL); Meets USP Class VI Biological Reactivity tests.\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eKey Benefits \u0026amp; Applications\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eBioburden Reduction:\u003c\/b\u003e Highly effective at reducing microbial loads in vaccine intermediates and plasma-derived proteins prior to final sterilizing filtration.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eMedia \u0026amp; Buffer Clarification:\u003c\/b\u003e Optimized for filtering serum-supplemented media and complex buffers where standard 0.2 µm filters typically \"blind\" or clog too quickly.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eParticulate Removal:\u003c\/b\u003e The depth-filtration characteristics of the MCE pre-filter layer make it excellent for removing colloidal matter and lipid aggregates from biological samples.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eFlexible Process Scaling:\u003c\/b\u003e The 9\/16\" hose barb design allows for rapid connection to standard silicone or TPE tubing, facilitating easy implementation in both R\u0026amp;D and pilot-scale production lines.\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003chr\u003e\n\u003cp style=\"margin: 0; font-size: 0.8em;\"\u003e\u003ci\u003eAll product names, logos, and brands are property of their respective owners.\u003c\/i\u003e\u003c\/p\u003e","brand":"Millipore","offers":[{"title":"Default Title","offer_id":44498184175868,"sku":"4375","price":96.67,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0627\/8463\/5132\/files\/millipore-filter-capsule-polysep-ii-opticap-xl-5-mce-02-um-filters-millipore-117876.jpg?v=1732586204","url":"https:\/\/lifesciencestrading.com\/products\/millipore-filter-capsule-polysep-ii-opticap-xl-5-mce-0-2-um","provider":"Life Sciences Trading","version":"1.0","type":"link"}