Millipore Filter Microplate 384 Well 0.45 um PVDF Pack of 10 Filter Plates

Millipore MZIPNNXU10 MultiScreen Filter Plate – 384-Well, 0.45 µm Hydrophobic PVDF

The Millipore MZIPNNXU10 MultiScreen is a high-throughput 384-well filter plate engineered for sophisticated sample preparation and protein-binding assays. It features a 0.45 µm hydrophobic PVDF (Polyvinylidene Fluoride) Durapore membrane, renowned for its exceptional protein binding capacity and high chemical resistance. Unlike hydrophilic plates, this hydrophobic membrane prevents aqueous solutions from passing through under gravity, allowing for extended incubations and multi-step reactions within the wells. Once the assay is complete, samples are recovered or cleared using a vacuum manifold or centrifugation. Built to standard ANSI/SLAS dimensions, the MZIPNNXU10 ensures seamless integration with automated liquid handling systems and plate readers, making it a critical consumable for drug discovery, clinical diagnostics, and proteomics workflows.

Technical Performance and Design

• Hydrophobic PVDF Membrane: The 0.45 µm Durapore membrane is ideal for applications requiring high protein binding, such as ELISpot or bead-based assays, and provides an effective barrier against premature aqueous filtration.

• Underdrain Design: Specifically engineered to prevent "wicking" or cross-talk between wells during filtration, ensuring that the filtrate from each of the 384 wells is directed accurately into a collection plate.

• Automation-Ready Construction: The rigid plate housing is designed for high-speed robotic grippers and automated workstations, maintaining dimensional stability even under high vacuum pressures.

• Low Extractables: The medical-grade materials used in the plate construction ensure that no plasticizers or contaminants leach into your samples, protecting the integrity of sensitive LC-MS/MS or HPLC downstream analysis.

Product Specifications

• Catalog Number: MZIPNNXU10

• Format: 384-Well Filter Plate

• Membrane Type: Hydrophobic PVDF (Durapore)

• Pore Size: 0.45 µm

• Plate Material: Pigmented Polyethylene / Polystyrene

• Sterility: Non-Sterile

Key Benefits & Applications

• Protein Binding Assays: Excellent for ELISpot and immunoassays where proteins must be immobilized onto the membrane surface for detection.

• Sample Cleanup & Clarification: Provides a high-throughput method for removing particulates from samples before injection into sensitive chromatography instruments.

• Bead-Based Assays: The 0.45 µm pore size effectively retains most microparticles and beads while allowing buffers to be washed through, simplifying complex washing protocols.

• Solvent Resistance: The PVDF membrane is highly resistant to a broad range of laboratory solvents, making it suitable for organic-phase extractions and chemical synthesis workflows.

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