{"product_id":"millipore-filter-pellicon-2-mini-cassette-with-10-kd-biomax-membrane","title":"Millipore Filter Pellicon 2 Mini Cassette with 10 kD Biomax Membrane","description":"\u003ch3\u003eMillipore P2B010A01 Pellicon® 2 Mini TFF Cassette (10 kD Biomax® PES, 0.1 m²)\u003c\/h3\u003e\n\u003cp\u003eThe Millipore P2B010A01 is a high-performance Tangential Flow Filtration (TFF) cassette engineered for the concentration, desalting, and buffer exchange of proteins, enzymes, and monoclonal antibodies. This unit utilizes the 10 kD Molecular Weight Cut-Off (MWCO) Biomax® modified Polyethersulfone (mPES) membrane, renowned for its high flux rates and exceptionally low non-specific binding characteristics. Designed with the \"A-Screen\" (coarse-channel) feed spacer, the P2B010A01 is optimized to handle higher protein concentrations and moderately viscous solutions that would typically clog finer screens. With a 0.1 m² effective filtration area, this Pellicon® 2 Mini cassette is the primary choice for process development and pilot-scale bioproduction.\u003c\/p\u003e\n\n\u003ch3\u003eTechnical Performance and Design\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eBiomax® mPES Membrane:\u003c\/b\u003e The modified polyethersulfone chemistry provides a hydrophilic surface that minimizes protein adsorption, ensuring high product recovery and easy cleaning for repeated use.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eA-Screen (Coarse Channel) Geometry:\u003c\/b\u003e The open-channel design provides a robust flow path that reduces the risk of gel-layer formation and channel plugging, making it ideal for processing high-titer cell culture harvests and concentrated protein streams.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eValidated 10 kD Retention:\u003c\/b\u003e Specifically engineered to provide sharp molecular weight cut-offs, making it ideal for the retention of antibodies (IgG) and other mid-sized proteins (~30 kDa to 150 kDa) while effectively removing salts and small metabolites.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eRugged Construction:\u003c\/b\u003e The Pellicon® 2 Mini format is built for durability and consistency, allowing for predictable scale-up to larger Pellicon® 2 industrial systems used in commercial manufacturing.\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eProduct Specifications\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eCatalog Number:\u003c\/b\u003e P2B010A01\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eMembrane Type:\u003c\/b\u003e Biomax® (modified Polyethersulfone \/ mPES)\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eMWCO:\u003c\/b\u003e 10 kD\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eFiltration Area:\u003c\/b\u003e 0.1 m² (1.1 ft²)\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eFeed Screen:\u003c\/b\u003e A-Screen (Coarse \/ High-Concentration)\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eFormat:\u003c\/b\u003e Pellicon® 2 Mini\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eOperating pH Range:\u003c\/b\u003e 1 to 14\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eSterilization:\u003c\/b\u003e Compatible with CIP (Clean-in-Place) and sanitization using Sodium Hydroxide (NaOH).\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eKey Benefits \u0026amp; Applications\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eProtein Concentration:\u003c\/b\u003e Rapidly reduces sample volume for antibodies and recombinant proteins while maintaining protein stability and activity.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eDiafiltration \u0026amp; Desalting:\u003c\/b\u003e Provides an efficient method for buffer exchange, removing residual solvents, or adjusting pH prior to final formulation.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eMonoclonal Antibody (mAb) Processing:\u003c\/b\u003e The 10 kD pore size is the industry standard for IgG concentration and formulation steps in biopharma.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eScalable Process Development:\u003c\/b\u003e Identical materials and fluid dynamics to production-scale Pellicon® 2 cassettes ensure that R\u0026amp;D results are directly transferable to full-scale manufacturing.\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003chr\u003e\n\u003cp style=\"margin: 0; font-size: 0.8em;\"\u003e\u003ci\u003eAll product names, logos, and brands are property of their respective owners.\u003c\/i\u003e\u003c\/p\u003e","brand":"Millipore","offers":[{"title":"Default Title","offer_id":44498198102268,"sku":"4406","price":779.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0627\/8463\/5132\/files\/millipore-filter-pellicon-2-mini-cassette-with-10-kd-biomax-membrane-filters-millipore-351576.jpg?v=1764825031","url":"https:\/\/lifesciencestrading.com\/products\/millipore-filter-pellicon-2-mini-cassette-with-10-kd-biomax-membrane","provider":"Life Sciences Trading","version":"1.0","type":"link"}