{"product_id":"millipore-filter-pellicon-xl-cassette-with-biomax-membrane-1000-kd","title":"Millipore Filter Pellicon XL Cassette with Biomax Membrane 1000 kD","description":"\u003ch3\u003eMillipore PXB01MC50 Pellicon® XL 50 TFF Cassette (1000 kD Biomax® PES, 50 cm²)\u003c\/h3\u003e\n\u003cp\u003eThe Millipore PXB01MC50 is a precision Tangential Flow Filtration (TFF) device engineered for laboratory-scale concentration, clarification, and fractionation of large biological particles. Featuring the 1000 kD Biomax® modified Polyethersulfone (mPES) membrane, this cassette provides high flux and ultra-low non-specific binding for exceptionally large biomolecules. The 1000 kD Molecular Weight Cut-Off (MWCO) represents the upper range of ultrafiltration, making it an ideal choice for the retention of viral vectors, large vaccines, and nanoparticles while allowing smaller proteins and contaminants to pass into the permeate. With a 50 cm² effective filtration area, the Pellicon® XL 50 is the industry standard for researchers developing high-recovery processes with minimal sample volumes.\u003c\/p\u003e\n\n\u003ch3\u003eTechnical Performance and Design\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003e1000 kD Biomax® mPES Membrane:\u003c\/b\u003e This ultra-high MWCO membrane is specifically modified to be hydrophilic, ensuring that large, sensitive biological entities do not adhere to the membrane surface, maximizing both yield and flux.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eLaboratory-Scale Efficiency:\u003c\/b\u003e The XL 50 format is optimized for volumes as low as 100 ml, featuring low hold-up volumes to ensure maximum product recovery of high-value experimental batches.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eTrue Linear Scalability:\u003c\/b\u003e Built with the same flow path materials and membrane chemistry as production-scale Pellicon® 2 and Pellicon® 3 cassettes, ensuring that process parameters developed at the 50 cm² scale can be reliably scaled up to full manufacturing levels.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eRobust Self-Contained Design:\u003c\/b\u003e Unlike larger cassettes that require heavy stainless steel holders, the Pellicon® XL 50 is a self-contained, easy-to-use module that integrates seamlessly into benchtop TFF systems.\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eProduct Specifications\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eCatalog Number:\u003c\/b\u003e PXB01MC50\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eMembrane Type:\u003c\/b\u003e Biomax® (modified Polyethersulfone \/ mPES)\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eMWCO:\u003c\/b\u003e 1000 kD (1 MDa)\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eFiltration Area:\u003c\/b\u003e 50 cm²\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eFormat:\u003c\/b\u003e Pellicon® XL 50\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eMax Operating Pressure:\u003c\/b\u003e 5.5 bar (80 psi) at 25 °C\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eRegulatory Compliance:\u003c\/b\u003e Meets USP Class VI Biological Test for Plastics; Non-pyrogenic.\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eKey Benefits \u0026amp; Applications\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eViral Vector Concentration:\u003c\/b\u003e Ideal for the concentration and diafiltration of large viral particles (such as Lentivirus or Adenovirus) where high recovery and rapid processing are essential.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eClarification of Cell Lysates:\u003c\/b\u003e Frequently used for the \"primary clarification\" step to remove large cellular debris and organelles while allowing the target protein to pass through the 1000 kD pores.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eNanoparticle \u0026amp; Liposome Processing:\u003c\/b\u003e Provides a gentle, low-shear environment for the washing and concentration of drug-delivery nanoparticles, maintaining particle size and polydispersity.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eVaccine Development:\u003c\/b\u003e Optimized for the purification of large antigens and virus-like particles (VLPs) from complex fermentation or cell culture streams.\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003chr\u003e\n\u003cp style=\"margin: 0; font-size: 0.8em;\"\u003e\u003ci\u003eAll product names, logos, and brands are property of their respective owners.\u003c\/i\u003e\u003c\/p\u003e","brand":"Millipore","offers":[{"title":"Default Title","offer_id":44498198397180,"sku":"4407","price":147.25,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0627\/8463\/5132\/files\/millipore-filter-pellicon-xl-cassette-with-biomax-membrane-1000-kd-filters-millipore-248741.jpg?v=1723234163","url":"https:\/\/lifesciencestrading.com\/products\/millipore-filter-pellicon-xl-cassette-with-biomax-membrane-1000-kd","provider":"Life Sciences Trading","version":"1.0","type":"link"}