Millipore MultiScreen Filter Plate 96 Well 0.45um PVDF Pack of 10 Filter Plates

Millipore MSIPS4510 MultiScreen® HTS IP Filter Plate (0.45 µm Hydrophobic PVDF, Sterile)

The Millipore MSIPS4510 is a high-performance 96-well filter plate specifically engineered for ELISPOT assays, protein binding studies, and cell-based screening. This plate features the Immobilon®-P hydrophobic PVDF membrane, which provides a high-surface-area matrix with exceptional protein binding capacity and low background noise. Designed for high-throughput (HTS) environments, the MSIPS4510 is built with rigid sidewalls for robotic handling and individually sealed wells to eliminate incubation crosstalk. Delivered gamma-sterilized with an included hydrophobic lid, this plate ensures a sterile environment for long-term cell culture or sensitive immunological assays. With its removable underdrain for easy access to the membrane, it is the gold standard for researchers performing cytokine profiling and vaccine development.

Technical Performance and Design

• Immobilon®-P PVDF Membrane: The 0.45 µm hydrophobic membrane is optimized for the immobilization of antibodies and proteins, ensuring high signal intensity and superior spot morphology in ELISPOT applications.

• Automation-Ready Construction: The rigid acrylic housing meets ANSI/SLAS 2004 plate specifications, providing the dimensional stability required for seamless integration with robotic liquid handlers and plate washers.

• Removable Underdrain: Features a patented underdrain design that can be removed for membrane visualization or punched out for radioactive scintillation counting.

• Zero Crosstalk: Wells are individually sealed to prevent lateral fluid migration and reagent carryover, ensuring the integrity of discrete assays across the entire 96-well array.

Product Specifications

• Catalog Number: MSIPS4510

• Membrane Material: Hydrophobic PVDF (Immobilon®-P)

• Pore Size: 0.45 µm

• Filtration Area: 0.28 cm² per well

• Well Volume: 300 µL Maximum / 50-250 µL Working Volume

• Sterility: Sterile (Gamma Irradiated)

• Compatibility: Vacuum Manifold, Centrifuge, and Automated Workstations.

• Packaging: Pack of 10 plates with lids.

Key Benefits & Applications

• ELISPOT Assays: The primary choice for quantifying antigen-specific immune responses at the single-cell level for vaccine and immunotherapy research.

• Protein Binding & Interaction: Ideal for ligand binding, bead-based assays, and dot blot applications requiring high protein retention.

• Whole Organism Visualization: Used in screening assays for small organisms where the clear acrylic plate allows for high-clarity optical analysis.

• Radioisotope Detection: Compatible with most scintillation cocktail systems for high-sensitivity detection of labeled molecules.

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