Millipore Polysep II Opticap XL 5 Capsule MCE .2 um

Millipore KGW3A05TT1 Opticap® XL 5 Capsule Filter (Milligard® G, 1.0 µm)

The Millipore KGW3A05TT1 is a high-capacity Opticap® XL 5 capsule filter engineered for the efficient prefiltration of solutions with high particulate loads and colloidal content. Featuring Milligard® G media—a gradient-density glass fiber matrix—this filter provides exceptional solids-handling capacity and high flow rates. The 1.0 µm nominal pore size is specifically designed to protect downstream sterilizing-grade membranes from premature fouling, making it an essential component in biopharmaceutical, wine/beverage, and fine chemical processing. The capsule's robust polypropylene housing and 1-1/2 inch Sanitary Flange (TC) connections ensure a secure, leak-proof integration into high-pressure sterile flow paths.

Technical Performance and Design

• Milligard® G Glass Fiber Media: The gradient-density glass fiber construction traps contaminants throughout the entire depth of the media, offering significantly higher throughput and dirt-holding capacity than standard surface filters.

• Opticap® XL 5 Configuration: A mid-sized capsule designed to bridge the gap between small laboratory filters and large-scale process cartridges, providing a generous 0.25 m² (nominal) filtration area.

• Low Extractable Design: Manufactured with high-purity polypropylene components and glass fiber media that meet stringent USP and FDA requirements for extractables, ensuring the purity of the filtered effluent.

• Rugged Sanitary Connections: Equipped with 1-1/2 inch (38 mm) Sanitary Flange (TC) inlet and outlet connections, compatible with standard pharmaceutical-grade tri-clamp fittings for rapid, aseptic installation.

Product Specifications

• Catalog Number: KGW3A05TT1

• Media Type: Milligard® G (Glass Fiber)

• Pore Size: 1.0 µm (Nominal)

• Device Size: Opticap® XL 5 (5-inch nominal length)

• Connections (Inlet/Outlet): 1-1/2 in. Sanitary Flange (TC)

• Housing Material: Polypropylene (PP)

• Max Operating Pressure: 5.5 bar (80 psi) @ 25 °C; 1.0 bar (15 psi) @ 80 °C

• Sterility: Non-Sterile (Autoclavable compatible)

Key Benefits & Applications

• Downstream Protection: Effectively removes bulk contaminants and colloids to extend the service life of expensive 0.22 µm and 0.1 µm sterile-grade final filters.

• Biopharmaceutical Clarification: Ideal for the pre-filtration of cell culture media, serum-containing buffers, and intermediate protein harvests where high capacity is required.

• High Flow Efficiency: The large surface area and depth-loading characteristics allow for rapid processing of viscous fluids or heavy-load solutions with minimal pressure drop.

• Regulatory Compliance: All component materials meet FDA Indirect Food Additive requirements (21 CFR 177-182) and USP Class VI Biological Tests for Plastics.

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