MP Biomedicals Lysing Matrix B 2 ml Pack of 100 Tubes

MP Biomedicals 6911100 Lysing Matrix B – 2 mL Tubes, 0.1 mm Silica Spheres

The MP Biomedicals 6911-100 (116911100) Lysing Matrix B is a highly specialized sample preparation consumable engineered for the efficient lysis of microorganisms, including Gram-positive and Gram-negative bacteria, yeast, fungi, and microalgae. Packaged in standard 2 mL microcentrifuge tubes, each tube is pre-filled with an optimized volume of ultra-fine 0.1 mm silica spheres. This exceptionally small bead diameter is critical for microbial extraction, as it creates a dense, high-friction grinding environment capable of shearing thick peptidoglycan and chitin cell walls that would otherwise resist chemical lysis or larger impaction beads. Built to withstand the extreme multidirectional velocity of the FastPrep-24 and other high-energy bead mills, Matrix B ensures rapid, complete homogenization for maximum nucleic acid and protein yields.

Technical Performance and Design

• 0.1 mm Silica Spheres: The ultra-fine silica beads provide an abrasive, high-shear environment perfectly scaled to the size of single-cell organisms, ensuring efficient mechanical disruption of tough cell walls.

• Impact-Resistant 2 mL Tubes: The heavy-duty plastic tubes and secure O-ring screw caps are engineered to endure severe G-forces, completely preventing leaks and aerosolization of potentially pathogenic microbial samples.

• Nuclease & Protease Free: Pre-filled and packaged under strict cleanroom conditions to ensure the matrix is free of DNase, RNase, and exogenous nucleic acids, which is vital for high-sensitivity microbiome and PCR downstream applications.

• Ready-to-Use Convenience: Eliminates the tedious, contamination-prone process of manually weighing and dispensing microscopic beads into individual tubes.

Product Specifications

• Catalog Number: 6911-100 (Manufacturer No. 116911100)

• Matrix Type: Matrix B (0.1 mm Silica Spheres)

• Tube Size: 2.0 mL (Skirted with O-ring screw cap)

• Target Samples: Bacteria, yeast, fungi, spores, biofilms, and microalgae.

• Quantity: 100 Tubes per pack

Key Benefits & Applications

• Microbiome & Metagenomics: The gold standard matrix for extracting comprehensive DNA profiles from environmental swabs, feces, and soil, ensuring even the most resilient microbial species are lysed and represented.

• Pathogen Detection: Provides the rapid, safe disruption needed for clinical diagnostics and food safety testing, fully containing the sample during the aggressive lysis step.

• High-Yield RNA Extraction: The extremely rapid processing time (often under 40 seconds) minimizes sample exposure to endogenous RNases, resulting in high-quality RNA for transcriptomics.

• Universal Bead Mill Compatibility: Fully compatible with the MP Biomedicals FastPrep series, as well as any standard laboratory bead beater that accepts 2 mL screw-cap tubes (e.g., Precellys, Omni, Qiagen TissueLyser).

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