MP Biomedicals Lysing Matrix D 15 ml Pack of 50 Tubes

MP Biomedicals 116933050 Lysing Matrix D – 15 mL Tubes, 1.4 mm Ceramic Spheres

The MP Biomedicals 116933050 Lysing Matrix D is a high-performance sample preparation consumable designed for the rapid and efficient homogenization of soft animal and plant tissues. Each 15 mL tube is pre-filled with an optimized volume of 1.4 mm ceramic (zirconium silicate) spheres. This specific bead density and geometry provide the perfect balance of impaction and shearing forces to lyse cellular structures without generating excessive heat that could compromise labile nucleic acids or proteins. Engineered to withstand the high-speed, 3D multidirectional motion of FastPrep instruments and other high-power bead beaters, these 15 mL tubes allow researchers to process large-volume samples—such as whole organs, pooled tissue biopsies, or high-density cell suspensions—in a single, enclosed step.

Technical Performance and Design

• 1.4 mm Ceramic Spheres: The smooth surface and high density of the zirconium silicate beads ensure rapid tissue disruption through mechanical shearing, preserving the integrity of high molecular weight DNA and sensitive enzymes.

• 15 mL Bulk Processing Format: The larger tube size accommodates sample masses ranging from 600 mg to 1.5 grams (or larger fluid volumes), dramatically increasing throughput for bulk extractions compared to standard 2 mL microcentrifuge tubes.

• Extreme Durability: The specialized plastic composition of the 15 mL tubes is engineered to withstand severe, high-velocity impact forces without cracking, leaking, or shedding plastic particulates into the sample.

• Pre-Filled & Ready-to-Use: Manufactured and packaged under stringent quality control, ensuring the matrix is free of nucleases, proteases, and exogenous nucleic acids, bypassing the need for manual bead measuring and decontamination.

Product Specifications

• Catalog Number: 116933050

• Matrix Type: Matrix D (1.4 mm Zirconium Silicate Ceramic Spheres)

• Tube Size: 15 mL (with leak-proof screw caps)

• Target Samples: Brain, liver, kidney, spleen, soft plant tissues, and cultured cells.

• Quantity: 50 Tubes per pack

Key Benefits & Applications

• High-Yield RNA/DNA Extraction: The rapid lysis (typically under 40 seconds) minimizes the time samples spend in a vulnerable state, maximizing the recovery and integrity of delicate RNA transcripts.

• Soft Tissue Optimization: Specifically validated for CNS (brain) tissue, liver, and delicate plant leaves where harsher, sharp-edged matrices (like garnet) would cause unnecessary sample shearing and foaming.

• Cross-Contamination Prevention: The single-use, closed-tube format eliminates the aerosol risks and tedious cleaning protocols associated with traditional rotor-stator homogenizers (e.g., Polytrons).

• Universal Bead Beater Compatibility: While optimized for the MP Biomedicals FastPrep-24 and FastPrep-96 systems equipped with 15 mL adapters, these tubes are fully compatible with any standard laboratory bead beater capable of holding 15 mL conical tubes.

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