MP Biomedicals Lysing Matrix D 4.5 ml Pack of 100 Tubes

MP Biomedicals 6973100 Lysing Matrix D – 4.5 mL TallPrep Tubes, 1.4 mm Ceramic Spheres

The MP Biomedicals 6973100 (116973100) Lysing Matrix D is a specialized sample preparation consumable engineered for the rapid homogenization of medium-volume soft animal and plant tissues. Packaged in 4.5 mL "TallPrep" tubes, this matrix bridges the gap between standard micro-volumes and bulk processing, easily accommodating sample masses up to 600 mg. Each tube is pre-filled with an optimized volume of 1.4 mm ceramic (zirconium silicate) spheres. The smooth surface and high density of these beads provide the ideal impaction force to shear delicate cellular structures—such as brain, liver, or soft plant leaves—without generating the degradative friction and heat associated with jagged matrices like garnet. Designed to withstand the intense multidirectional forces of high-speed bead beaters, these tubes ensure safe, aerosol-free tissue disruption for the highest quality downstream DNA, RNA, and protein extraction.

Technical Performance and Design

• 1.4 mm Zirconium Silicate Spheres: The ceramic beads deliver highly efficient, non-destructive shearing forces, preserving the integrity of heat-sensitive, high molecular weight nucleic acids and labile enzymes.

• 4.5 mL TallPrep Format: Provides the crucial extra headspace needed for medium-sized samples and adequate lysis buffer volumes, preventing the "packing" effect that stalls homogenization in smaller 2 mL tubes.

• Impact-Resistant Construction: The heavy-duty plastic tubes and secure screw caps are engineered to endure severe G-forces without cracking, leaking, or shedding particulates into the lysate.

• Certified Nuclease-Free: Pre-filled and packaged under strict cleanroom conditions, ensuring the matrix is completely free of DNase, RNase, proteases, and exogenous nucleic acids right out of the box.

Product Specifications

• Catalog Number: 6973100 (Manufacturer No. 116973100)

• Matrix Type: Matrix D (1.4 mm Ceramic Spheres)

• Tube Size: 4.5 mL (TallPrep format with screw cap)

• Target Samples: Brain, liver, kidney, spleen, soft plant tissues, and high-density cultured cells.

• Quantity: 100 Tubes per pack

Key Benefits & Applications

• Optimized for Soft Tissues: The preferred matrix for neuroscience and oncology research, effectively lysing CNS tissue and soft tumors without the excessive foaming caused by harsher beads.

• Rapid Processing Times: Capable of reducing complex tissue networks to a uniform homogenate in 40 seconds or less, minimizing the time samples are exposed to endogenous nucleases.

• Aerosol Containment: The completely enclosed, single-use tube eliminates the risk of cross-contamination and the hazardous aerosolization of pathogenic or viral samples.

• Instrument Compatibility: Perfectly suited for the MP Biomedicals FastPrep-24 system when equipped with the TallPrep adapter, as well as other high-power bead beaters that accept 4.5 mL or 5 mL tubes.

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