{"product_id":"novasep-filter-manifold-sius-low-volume-plate-insert","title":"Novasep Filter Manifold SIUS Low Volume Plate Insert","description":"\u003ch3\u003eNovasep \/ Sartorius TFPLS-LVFL SIUS™ Low Volume Plate Insert\u003c\/h3\u003e\n\u003cp\u003eThe Novasep TFPLS-LVFL is a precision-engineered manifold component designed for the SIUS™ Tangential Flow Filtration (TFF) platform. This Low Volume Plate Insert is specifically developed to optimize the fluid path within the TFF holder, significantly reducing the internal holdup (dead) volume of the system. By minimizing the volume of the manifold channels, this insert allows for higher concentration factors and ensures maximum recovery of high-value biological products, even when processing small starting volumes. Manufactured from high-durability, chemically resistant materials, the TFPLS-LVFL is an essential tool for process development and pilot-scale purification where sample conservation and yield are paramount.\u003c\/p\u003e\n\n\u003ch3\u003eTechnical Performance and Design\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eMinimized Holdup Volume:\u003c\/b\u003e The internal flow channels are precision-machined to the smallest possible diameter consistent with efficient flux, allowing for the processing of low-volume batches (down to a few milliliters) without significant loss.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eOptimized Flow Dynamics:\u003c\/b\u003e Engineered to maintain consistent pressure and sweep velocity across the TFF membrane surface, ensuring that the low-volume optimization does not compromise filtration efficiency or product stability.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eSeamless SIUS™ Integration:\u003c\/b\u003e Designed for a perfect \"drop-in\" fit within the standard SIUS™ TFF manifold and plate-and-frame holders, requiring no specialized tools for installation or removal.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eHigh Purity \u0026amp; Compatibility:\u003c\/b\u003e Constructed from materials that meet stringent biopharmaceutical requirements, offering broad chemical compatibility with common buffers, cleaning agents, and sanitization protocols (CIP).\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eProduct Specifications\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eCatalog Number:\u003c\/b\u003e TFPLS-LVFL\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eSystem Compatibility:\u003c\/b\u003e Novasep \/ Sartorius SIUS™ TFF Systems\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003ePart Type:\u003c\/b\u003e Low Volume Plate Insert \/ Manifold Plate\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eMaterial:\u003c\/b\u003e High-Performance Polymer \/ Stainless Steel (depending on specific revision)\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eFunction:\u003c\/b\u003e Holdup volume reduction for small-scale concentration and diafiltration.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eCleaning:\u003c\/b\u003e Autoclavable and compatible with standard CIP (Clean-in-Place) procedures.\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eKey Benefits \u0026amp; Applications\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eHigh-Value Protein Recovery:\u003c\/b\u003e Ideal for researchers working with expensive monoclonal antibodies, recombinant proteins, or rare enzymes where every milliliter of product counts.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eProcess Development:\u003c\/b\u003e Allows for the determination of final concentration limits during R\u0026amp;D without requiring large quantities of starting material.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eViral Vector Concentration:\u003c\/b\u003e Used in gene therapy workflows (AAV\/Lentivirus) to reach the extremely high concentrations required for downstream formulation.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eEnhanced Concentrating Power:\u003c\/b\u003e By reducing the minimum loop volume of the TFF system, this insert enables researchers to push the concentration factor well beyond what is possible with standard manifold plates.\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003chr\u003e\n\u003cp style=\"margin: 0; font-size: 0.8em;\"\u003e\u003ci\u003eAll product names, logos, and brands are property of their respective owners. \u003c\/i\u003e\u003c\/p\u003e","brand":"Novasep","offers":[{"title":"Default Title","offer_id":44498198692092,"sku":"4410","price":228.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0627\/8463\/5132\/files\/novasep-filter-manifold-sius-low-volume-plate-insert-other-valves-manifolds-novasep-816676.jpg?v=1788312926","url":"https:\/\/lifesciencestrading.com\/products\/novasep-filter-manifold-sius-low-volume-plate-insert","provider":"Life Sciences Trading","version":"1.0","type":"link"}