Novasep Sius-LS TFF Cassette HyS 50 kD 0.01 m2 Sealed Box

The Novasep XP050LP1L Sius-LS TFF Cassette is a specialized tangential flow filtration (TFF) device designed for laboratory-scale purification and concentration of biomolecules. This cassette utilizes a HyStream Low Fouling mPES membrane with a 50 kD (kilodalton) molecular weight cutoff, which is optimized for high-performance and low non-specific binding. The membrane material, mPES (modified polyethersulfone), is known for its chemical resistance and high flux, ensuring efficient filtration.

The cassette has a filtration area of 0.01 m² and features a low-profile screen channel, a design that helps to minimize shear stress on sensitive molecules and reduce fouling during the filtration process. TFF is a technique where the feed stream flows tangentially across the membrane, which helps prevent the buildup of molecules on the membrane surface, leading to higher throughput and longer process times.

This Novasep Sius-LS TFF cassette is a vital tool for biopharmaceutical research and process development, used for applications such as protein concentration, buffer exchange, and diafiltration. Its design is a key to achieving high yields and purity in a variety of bioprocessing workflows.