Pall Filter FP-200 Membrane Filter 0.2 um 47 mm Total of 75 Filters

Pall 66477 FP-Vericel (FP-200) PVDF Membrane Filter – 0.2 µm, 47 mm

The Pall 66477 is a high-performance, 47 mm FP-Vericel membrane filter disc engineered for rigorous analytical sample preparation and mobile phase degassing. Constructed from hydrophilic Polyvinylidene Fluoride (PVDF), it features an absolute 0.2 µm pore size that reliably removes fine particulate matter and microbial contaminants from both aqueous and organic solvent-based solutions. Certified specifically for High-Performance Liquid Chromatography (HPLC), this membrane yields incredibly low levels of UV-absorbing extractables, guaranteeing that your downstream analytical results are not compromised by leachable background noise. Unlike standard hydrophobic PTFE filters, the FP-Vericel PVDF requires no pre-wetting with alcohols before filtering aqueous buffers, saving researchers valuable time during routine solvent preparation.

Technical Performance and Design

• Hydrophilic PVDF Matrix: The inherently water-wettable FP-Vericel material allows for the immediate, high-flow filtration of aqueous solutions without the need for complex pre-wetting steps, while remaining highly resistant to shrinking or cracking.

• HPLC Certified for Low Extractables: Rigorously quality-tested to ensure it does not release interfering UV-absorbing extractables into the filtrate, providing clean, stable baselines for sensitive liquid chromatography detectors.

• 0.2 µm Sterilizing Grade: The absolute 0.2-micron pore size effectively traps fine particulates and bio-burden, protecting expensive downstream analytical equipment—such as HPLC columns and mass spectrometer injection valves—from premature fouling.

• Broad Chemical Compatibility: Offers exceptional resistance to a wide range of common laboratory solvents, including methanol, acetonitrile, esters, and mild acids. (Note: Not recommended for use with acetone, DMF, DMSO, or strong bases >6N).

Product Specifications

• Catalog Number: 66477

• Membrane Material: FP-Vericel (Hydrophilic Polyvinylidene Fluoride / PVDF)

• Pore Size: 0.2 µm

• Diameter: 47 mm

• Sterility: Non-Sterile (Autoclavable)

Key Benefits & Applications

• Mobile Phase Filtration: The industry standard for simultaneously filtering and degassing HPLC and UHPLC mobile phase solvents when used in combination with a standard 47 mm glass or magnetic vacuum filtration funnel.

• Analytical Sample Prep: Ensures that complex analytical standards and biological samples are perfectly clarified before injection, extending the lifespan of expensive chromatography columns.

• Low Protein Binding: PVDF is known for its relatively low affinity for proteins compared to nylon or nitrocellulose, making it a viable option for filtering dilute proteinaceous samples without significant yield loss.

• Thermal Stability: The durable polymer matrix can safely withstand standard steam autoclave sterilization cycles if a sterile filtrate is required for downstream tissue culture applications.

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