{"product_id":"phenomenex-strata-x-c-microplate-10-mg-strong-cation-each-well-96-well","title":"Phenomenex Strata-X-C Microplate 10 mg Strong Cation Each Well 96 Well - 2 Plates","description":"\u003ch3\u003ePhenomenex Strata-X-C SPE Microplate – 10 mg\/well, Strong Cation, 96-Well\u003c\/h3\u003e\n\u003cp\u003eThe Phenomenex 8E-S029-AGB is a high-performance Solid Phase Extraction (SPE) microplate engineered for the rapid, high-throughput isolation of weakly basic compounds from low-volume samples. Each well in the 96-well polypropylene manifold contains 10 mg of Strata-X-C, a 33 µm polymeric strong cation-exchange sorbent. Unlike traditional silica-based sorbents, this rugged polymeric backbone resists deconditioning if accidentally dried out during the conditioning or washing steps, entirely eliminating the risk of lost sample recoveries. The uniquely modified mixed-mode chemistry uniformly bonds a sulfonic acid ligand to the polymer, offering three mechanisms of retention (strong cation exchange, pi-pi bonding, and hydrophobic interactions). This strong ionic binding allows researchers to aggressively wash away matrix interferences using 100% organic solvents, resulting in ultra-clean extracts that significantly improve LC-MS\/MS sensitivity while utilizing minimal elution volumes due to the highly efficient 10 mg sorbent mass.\u003c\/p\u003e\n\n\u003ch3\u003eTechnical Performance and Design\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eMixed-Mode Retention:\u003c\/b\u003e Synergistically combines strong cation-exchange capabilities with reversed-phase (hydrophobic and pi-pi) bonding, providing unparalleled selectivity and retention for weakly basic analytes (pKa 8-10).\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003e100% Organic Wash Capability:\u003c\/b\u003e The strong ionic binding of target bases enables the use of 100% organic solvents during the wash step, effectively stripping away neutral interferences, phospholipids, and particulates without analyte breakthrough.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eLow Bed Weight (10 mg):\u003c\/b\u003e The efficient 10 mg sorbent mass is optimized for smaller sample sizes, allowing researchers to utilize highly concentrated, low-volume elution steps that often completely bypass the need for solvent evaporation and reconstitution before LC-MS\/MS injection.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eHigh-Throughput 96-Well Format:\u003c\/b\u003e Built into a standard SBS-footprint polypropylene plate, making it seamlessly compatible with automated liquid handling robots, positive pressure manifolds, and 96-well vacuum blocks for rapid batch processing.\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eProduct Specifications\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eCatalog Number:\u003c\/b\u003e 8E-S029-AGB\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eFormat:\u003c\/b\u003e 96-Well Plate\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003ePhase\/Chemistry:\u003c\/b\u003e Strata-X-C (Polymeric Strong Cation Mixed Mode)\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eParticle Size:\u003c\/b\u003e 33 µm (85 Å Pore Size)\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eSorbent Mass:\u003c\/b\u003e 10 mg per well\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eHousing Material:\u003c\/b\u003e Polypropylene\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eTarget Analytes:\u003c\/b\u003e Weak Bases (pKa 8-10)\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eKey Benefits \u0026amp; Applications\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eClinical \u0026amp; Toxicological Assays:\u003c\/b\u003e The industry standard for the high-throughput extraction of basic pharmaceutical compounds, drugs of abuse, and metabolites from complex biological fluids like blood plasma, serum, and urine.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eLow-Volume Efficiency:\u003c\/b\u003e Perfect for pediatric testing, murine (mouse) models, or any diagnostic assay where the available biological sample volume is strictly limited.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eLC-MS\/MS Optimization:\u003c\/b\u003e Highly effective at stripping away phospholipids and salts, preventing the severe ion-suppression effects that frequently plague sensitive mass spectrometry detectors.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eRobust Method Reliability:\u003c\/b\u003e The advanced polymeric backbone prevents the sorbent from collapsing, ensuring that accidental drying under a vacuum manifold will not compromise sensitive extraction recoveries.\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003chr\u003e\n\u003cp style=\"margin: 0; font-size: 0.8em;\"\u003e\u003ci\u003eAll product names, logos, and brands are property of their respective owners.\u003c\/i\u003e\u003c\/p\u003e","brand":"Phenomenex","offers":[{"title":"Default Title","offer_id":44789843034364,"sku":"6012","price":66.88,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0627\/8463\/5132\/files\/phenomenex-strata-x-c-microplate-10-mg-strong-cation-each-well-96-well-2-plates-filters-phenomenex-383603.jpg?v=1713476227","url":"https:\/\/lifesciencestrading.com\/products\/phenomenex-strata-x-c-microplate-10-mg-strong-cation-each-well-96-well","provider":"Life Sciences Trading","version":"1.0","type":"link"}