{"product_id":"phenomenex-strata-x-cw-microplate-30-mg-weak-cation-96-well","title":"Phenomenex Strata-X-CW Microplate 30 mg Weak Cation 96 Well 2 Sealed Plates","description":"\u003ch3\u003ePhenomenex Strata-X-CW SPE Microplate – 30 mg\/well, Weak Cation, 96-Well\u003c\/h3\u003e\n\u003cp\u003eThe Phenomenex 8E-S035-TGB is a high-performance Solid Phase Extraction (SPE) microplate engineered for the rapid, high-throughput isolation of strongly basic compounds. Each well in the 96-well polypropylene manifold contains 30 mg of Strata-X-CW, a 33 µm polymeric weak cation-exchange sorbent. Unlike traditional silica-based sorbents, this rugged polymeric backbone resists deconditioning if accidentally dried out during the conditioning or washing steps, entirely eliminating the risk of lost sample recoveries. The uniquely modified mixed-mode chemistry uniformly bonds a carboxylic acid ligand to the polymer, offering three mechanisms of retention (weak cation exchange, pi-pi bonding, and hydrophobic interactions). This strong ionic binding allows researchers to aggressively wash away matrix interferences using 100% organic solvents, resulting in ultra-clean extracts that significantly improve LC-MS\/MS sensitivity.\u003c\/p\u003e\n\n\u003ch3\u003eTechnical Performance and Design\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eMixed-Mode Retention:\u003c\/b\u003e Synergistically combines weak cation-exchange capabilities with reversed-phase (hydrophobic and pi-pi) bonding, providing unparalleled selectivity and retention for strongly basic analytes (pKa \u0026gt; 8).\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003e100% Organic Wash Capability:\u003c\/b\u003e The strong ionic binding of target bases enables the use of 100% organic solvents during the wash step, effectively stripping away neutral interferences, phospholipids, and particulates without analyte breakthrough.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eResistant to Drying:\u003c\/b\u003e The advanced polymeric backbone prevents the sorbent from collapsing, ensuring that accidental drying under a vacuum manifold will not compromise sensitive extraction recoveries.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eHigh-Throughput 96-Well Format:\u003c\/b\u003e Built into a standard SBS-footprint polypropylene plate, making it seamlessly compatible with automated liquid handling robots, positive pressure manifolds, and 96-well vacuum blocks for rapid batch processing.\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eProduct Specifications\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eCatalog Number:\u003c\/b\u003e 8E-S035-TGB\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eFormat:\u003c\/b\u003e 96-Well Plate\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003ePhase\/Chemistry:\u003c\/b\u003e Strata-X-CW (Polymeric Weak Cation Mixed Mode)\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eParticle Size:\u003c\/b\u003e 33 µm (85 Å Pore Size)\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eSorbent Mass:\u003c\/b\u003e 30 mg per well\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eHousing Material:\u003c\/b\u003e Polypropylene\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eTarget Analytes:\u003c\/b\u003e Strong Bases and Quaternary Amines (pKa \u0026gt; 8)\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eKey Benefits \u0026amp; Applications\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eClinical \u0026amp; Toxicological Assays:\u003c\/b\u003e The industry standard for the high-throughput extraction of strongly basic pharmaceutical compounds, drugs of abuse, and metabolites from complex biological fluids like blood plasma, serum, and urine.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eLC-MS\/MS Optimization:\u003c\/b\u003e Highly effective at stripping away phospholipids and salts, preventing the severe ion-suppression effects that frequently plague sensitive mass spectrometry detectors.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eEnvironmental Testing:\u003c\/b\u003e Allows for the rapid concentration of trace-level strongly basic contaminants from municipal water and soil extracts.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eSolvent Switching \u0026amp; Concentration:\u003c\/b\u003e Allows researchers to elute target compounds directly into a minimal volume of mass-spec friendly solvent, bypassing time-consuming evaporation and reconstitution steps.\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003chr\u003e\n\u003cp style=\"margin: 0; font-size: 0.8em;\"\u003e\u003ci\u003eAll product names, logos, and brands are property of their respective owners.\u003c\/i\u003e\u003c\/p\u003e","brand":"Phenomenex","offers":[{"title":"Default Title","offer_id":44789842936060,"sku":"6011","price":182.88,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0627\/8463\/5132\/files\/phenomenex-strata-x-cw-microplate-30-mg-weak-cation-96-well-2-sealed-plates-filters-phenomenex-706307.jpg?v=1713475116","url":"https:\/\/lifesciencestrading.com\/products\/phenomenex-strata-x-cw-microplate-30-mg-weak-cation-96-well","provider":"Life Sciences Trading","version":"1.0","type":"link"}