Phenomenex Strata-X Filter Microplate 10 mg Polymeric Reversed Phase Single Sealed Plate

Phenomenex Strata-X Polymeric SPE Microplate – 10 mg/well, Reversed Phase, 96-Well

The Phenomenex 8E-S100-AGB is a high-performance Solid Phase Extraction (SPE) microplate engineered for the rapid, high-throughput isolation of a broad spectrum of target analytes from low-volume samples. Each well in the 96-well polypropylene manifold contains 10 mg of Strata-X, a 33 µm polymeric reversed-phase sorbent. Unlike traditional silica-based C18 sorbents, this rugged polymeric backbone resists deconditioning if accidentally dried out during the conditioning or washing steps, entirely eliminating the risk of lost sample recoveries. The uniquely modified surface chemistry offers three mechanisms of retention (pi-pi, hydrogen bonding, and hydrophobic interactions), allowing researchers to aggressively wash away matrix interferences. This results in ultra-clean extracts that significantly improve LC-MS/MS sensitivity while utilizing minimal elution volumes due to the highly efficient 10 mg sorbent mass.

Technical Performance and Design

• Universal Retention Mechanisms: The specially modified styrene divinylbenzene polymer tightly retains a massive variety of neutral, basic, and acidic compounds, making it the ideal starting point for broad SPE method development.

• Low Bed Weight (10 mg): The efficient 10 mg sorbent mass is optimized for smaller sample sizes, allowing researchers to utilize highly concentrated, low-volume elution steps that often completely bypass the need for solvent evaporation and reconstitution before LC-MS/MS injection.

• Resistant to Drying: The advanced polymeric backbone prevents the sorbent from collapsing, ensuring that accidental drying under vacuum will not compromise sensitive extraction recoveries or waste valuable samples.

• High-Throughput 96-Well Format: Built into a standard SBS-footprint polypropylene plate, making it seamlessly compatible with automated liquid handling robots, positive pressure manifolds, and standard vacuum blocks for rapid batch processing.

Product Specifications

• Catalog Number: 8E-S100-AGB

• Format: 96-Well Plate

• Phase/Chemistry: Strata-X (Polymeric Reversed Phase)

• Particle Size: 33 µm (85 Å Pore Size)

• Sorbent Mass: 10 mg per well

• Housing Material: Polypropylene

• Target Analytes: Neutrals, Acids, and Bases

Key Benefits & Applications

• Low-Volume Efficiency: Perfect for pediatric testing, murine (mouse) models, or any diagnostic assay where the available biological sample volume is strictly limited.

• Clinical & Toxicological Assays: The industry standard for the high-throughput extraction of drugs of abuse, metabolites, and biomarkers from complex biological fluids like blood plasma, serum, and urine.

• LC-MS/MS Optimization: Highly effective at stripping away phospholipids, salts, and particulates, preventing the ion-suppression effects that frequently plague sensitive mass spectrometry detectors.

• Solvent Switching & Concentration: Allows researchers to elute target compounds directly into a minimal volume of mass-spec friendly solvent, bypassing time-consuming evaporation and reconstitution steps.

All product names, logos, and brands are property of their respective owners.