Phenomenex Strata-X Microplate Polymeric Reversed Phase 96 Well Sealed Plate

Phenomenex Strata-X Polymeric SPE Microplate – 30 mg/well, Reversed Phase, 96-Well

The Phenomenex 8E-S100-TGB is a high-performance Solid Phase Extraction (SPE) microplate engineered for the rapid, high-throughput isolation of a broad spectrum of target analytes. Each well in the 96-well polypropylene manifold contains 30 mg of Strata-X, a 33 µm polymeric reversed-phase sorbent. Unlike traditional silica-based C18 sorbents, this rugged polymeric backbone resists deconditioning if accidentally dried out during the conditioning or washing steps, entirely eliminating the risk of lost sample recoveries. The uniquely modified surface chemistry offers three mechanisms of retention (pi-pi, hydrogen bonding, and hydrophobic interactions), allowing researchers to aggressively wash away matrix interferences like proteins and salts. This results in ultra-clean extracts that significantly improve LC-MS/MS sensitivity and drastically extend the lifespan of analytical chromatography columns.

Technical Performance and Design

• Universal Retention Mechanisms: The specially modified styrene divinylbenzene polymer tightly retains a massive variety of neutral, basic, and acidic compounds, making it the ideal starting point for broad SPE method development.

• Resistant to Drying: The advanced polymeric backbone prevents the sorbent from collapsing, ensuring that accidental drying under vacuum will not compromise sensitive extraction recoveries or waste valuable samples.

• High-Throughput 96-Well Format: Built into a standard SBS-footprint polypropylene plate, making it seamlessly compatible with automated liquid handling robots, positive pressure manifolds, and standard vacuum blocks for rapid batch processing.

• 33 µm Polymeric Particle: The highly uniform particle size provides excellent flow characteristics and a massive surface area, resulting in highly reproducible extractions, concentrated analyte recoveries, and zero channeling effects.

Product Specifications

• Catalog Number: 8E-S100-TGB

• Format: 96-Well Plate

• Phase/Chemistry: Strata-X (Polymeric Reversed Phase)

• Particle Size: 33 µm

• Sorbent Mass: 30 mg per well

• Housing Material: Polypropylene

• Target Analytes: Neutrals, Acids, and Bases

Key Benefits & Applications

• Clinical & Toxicological Assays: The industry standard for the high-throughput extraction of drugs of abuse, metabolites, and biomarkers from complex biological fluids like blood plasma, serum, and urine.

• LC-MS/MS Optimization: Highly effective at stripping away phospholipids, salts, and particulates, preventing the ion-suppression effects that frequently plague sensitive mass spectrometry detectors.

• Environmental Testing: Allows for the rapid concentration of trace-level organic contaminants (like pesticides and pharmaceuticals) from municipal water and soil extracts.

• Solvent Switching & Concentration: Allows researchers to elute target compounds directly into a minimal volume of mass-spec friendly solvent, bypassing time-consuming evaporation and reconstitution steps.

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