Repligen ACBT-500-D Disposable Bottle 3 Port 500 mL
Repligen ACBT-500-D 500 ml Process Bottle (3-Port Cap Assembly)
The Repligen ACBT-500-D is a high-purity 500 ml reservoir system engineered for critical fluid management in biopharmaceutical development and pilot-scale research. This specialized vessel is equipped with a factory-integrated 3-port cap assembly, facilitating multiple simultaneous fluid paths—such as aspiration, recirculation, and venting—within a completely closed system. Designed to minimize the risk of environmental contamination, the ACBT-500-D is an essential component for aseptic liquid handling, particularly in tangential flow filtration (TFF), perfusion, and automated sampling workflows. The robust bottle construction and precision-engineered porting ensure reliable performance under vacuum or low-pressure conditions, providing a secure environment for high-value biological intermediates.
Technical Performance and Design
Integrated 3-Port Management: The cap assembly provides three dedicated access points, allowing for seamless integration of inlet lines, outlet lines, and air-vent filters without breaching the sterile barrier.
Closed-System Aseptic Transfer: Engineered to eliminate open-air pouring, this assembly significantly reduces bioburden risks during the movement of media, buffers, or cell harvests.
High-Purity Materials: Manufactured from medical-grade, USP Class VI compliant polymers, ensuring ultra-low extractables and excellent chemical compatibility with common bioprocessing reagents.
Scale-Up Compatibility: The 500 ml volume is optimized for benchtop process development, providing a consistent platform for transitioning from discovery-scale research to clinical manufacturing trials.
Product Specifications
Catalog Number: ACBT-500-D
Volume Capacity: 500 ml
Port Configuration: 3-Port Cap (typically includes internal dip tubes for fluid draw).
Material: High-purity Polypropylene or PETG (please verify physical unit material).
Connection Type: Barb or Luer-style ports (depending on specific tubing assembly attached).
Sterility: Non-sterile (Autoclavable) or Pre-sterilized (please verify packaging status).
Key Benefits & Applications
KrosFlo TFF Systems: Acts as a centralized feed and recirculation reservoir for the concentration and diafiltration of proteins, antibodies, and viral vectors.
Continuous Bioprocessing: Ideal for use as a sterile media feed bottle or permeate collection vessel in continuous cell culture and perfusion setups.
Aseptic Sampling: Provides a secure manifold for withdrawing samples from a bioreactor or process loop without compromising the integrity of the primary batch.
Buffer Management: Used for the sterile storage and delivery of precisely formulated buffers in automated chromatography and filtration workflows.
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Please note that Life Sciences Trading is not a factory-authorized distributor of the products listed in this store. The items have been acquired as surplus from leading life sciences companies.