Repligen Bottle 250 ml with 3 Port Cap

Repligen ACBT-250-D 250 ml Disposable Bottle (3-Port Aseptic Cap)

The Repligen ACBT-250-D is a premium single-use reservoir engineered for high-purity fluid management in biopharmaceutical and laboratory environments. Featuring a 250 ml capacity and a versatile 3-port cap design, this bottle facilitates closed-system fluid transfers, sampling, and reagent additions without environmental exposure. The ACBT series is specifically designed to meet the rigorous demands of cell culture and downstream processing, where maintaining a sterile flow path is paramount. By utilizing a disposable format, the ACBT-250-D significantly reduces the risk of cross-contamination and streamlines workflow efficiency by eliminating the time-consuming requirements of traditional glass cleaning and autoclave validation.

Technical Performance and Design

• Closed-System 3-Port Configuration: The integrated 3-port cap allows for the simultaneous connection of fill lines, vent filters, and sampling manifolds, maintaining an aseptic environment throughout the duration of the process.

• High-Purity Materials: Constructed from medical-grade, USP Class VI compliant polymers that offer exceptionally low extractables and leachables, ensuring the stability of sensitive biological molecules and media.

• Universal Port Compatibility: Designed to interface with standard single-use tubing (typically silicone or TPE), the ports provide secure, leak-proof attachment points for pumps, sensors, and aseptic connectors.

• Ergonomic & Robust Design: Despite its disposable nature, the bottle features a robust wall thickness and a stable base, designed to withstand the physical demands of benchtop bioprocessing and storage.

Product Specifications

• Catalog Number: ACBT-250-D

• Volume Capacity: 250 ml

• Cap Type: 3-Port Aseptic Screw Cap

• Material (Bottle): High-Purity Polyethylene / Polypropylene (ADCF)

• Material (Ports): Polypropylene with Silicone seals

• Sterility: Disposable (Available Gamma Irradiated / Ready-to-Use)

• Regulatory Compliance: USP Class VI; Non-cytotoxic; Animal-Derived Component Free (ADCF).

Key Benefits & Applications

• Aseptic Sampling: Perfect for taking intermediate samples from a bioreactor or chromatography system without breaking the sterile barrier.

• Media & Buffer Prep: Ideal for preparing and storing small-volume sterile buffers or concentrated media supplements used in perfusion or fed-batch cultures.

• Feed Reservoir: Functions as a reliable feed bottle for peristaltic pumps in small-scale fermentation or cell culture setups (1L scale and below).

• Process Standardization: The predictable extractable profile and pre-validated sterility help researchers standardize fluid paths across different stages of drug development.

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