Repligen KrossFlo Fitting 1.5 in Sanitary to 3/8" 90 deg Hose Barb Lot of 6

Repligen ProConnex® KrosFlo® Fitting – 1-1/2" TC x 3/8" HB with Female Luer Lock

The Repligen ACPX-SM3-06N is a high-performance, multi-port fitting designed to streamline Tangential Flow Filtration (TFF) and bioprocessing flow paths. Specifically engineered for the KrosFlo® KR2i and TFF systems, this component integrates a 1-1/2 inch Sanitary Flange (TC) with a 3/8 inch Hose Barb and an auxiliary Female Luer Lock (FLL) port. This "all-in-one" design allows for the direct attachment of hollow fiber modules to process tubing while simultaneously providing a secure port for pressure transducers, sampling, or reagent addition. Molded from medical-grade polysulfone, this fitting ensures low leachables and high chemical compatibility for sensitive biopharmaceutical applications.

Technical Performance and Design

• Integrated 3-Way Connectivity: Eliminates the need for traditional tube-to-tube adapters and complicated "tee" junctions, reducing the risk of leaks and minimizing hold-up volume in the fluid path.

• Polysulfone Construction: Manufactured from the same low-extractable polysulfone used in high-end hollow fiber module housings, ensuring material consistency and superior biocompatibility throughout the flow path.

• Auxiliary Female Luer Port: The integrated FLL port is designed for the seamless connection of pressure sensors (such as the Konduit or KrosFlo sensors) or for sterile sampling via a syringe without breaking the closed-system integrity.

• Precision Sanitary Interface: The 1-1/2 inch TC flange is engineered for a perfect fit with standard sanitary clamps and gaskets, providing a high-pressure seal suitable for filtration and concentration workflows.

Product Specifications

• Catalog Number: ACPX-SM3-06N

• Connection A: 1-1/2" Sanitary Flange (TC)

• Connection B: 3/8" Hose Barb (HB)

• Auxiliary Port: Female Luer Lock (FLL)

• Material: Polysulfone (Molded)

• Sterility: Non-Sterile (Autoclavable; Gamma Compatible)

• Packaging: Available as individual units or in packs of 6.

Key Benefits & Applications

• TFF Process Simplification: Ideal for connecting the feed or retentate ports of a hollow fiber module to peristaltic pump tubing while maintaining a port for real-time pressure monitoring.

• Minimized Hold-up Volume: The compact, molded design reduces "dead space" compared to multi-component assemblies, which is critical for maximizing recovery of high-value proteins or viral vectors.

• Aseptic Sampling & Dosing: The luer lock port facilitates the sterile addition of diafiltration buffers or the removal of samples for confluence and concentration analysis during the run.

• Rugged Durability: Engineered to withstand the mechanical stresses of high-flow bioprocessing and repeated sterilization cycles without cracking or dimensional drift.

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