{"product_id":"repligen-midikros-hollow-fiber-filter-mpes-750-kda-1","title":"Repligen MidiKros Hollow Fiber Filter mPES 750 kDa","description":"\u003ch3\u003eRepligen MidiKros D06-E750-05-S Hollow Fiber Filter – Sterile mPES, 750 kDa, 370 cm2\u003c\/h3\u003e\n\u003cp\u003eThe Repligen D06-E750-05-S is a precision-engineered MidiKros hollow fiber module designed for laboratory-scale Tangential Flow Filtration (TFF). Utilizing proprietary modified Polyethersulfone (mPES) membrane technology, this filter offers high flux rates and exceptional product recovery with minimal non-specific binding. This \"S\" designation indicates that the module is supplied Gamma Irradiated (Sterile), providing a ready-to-use, closed-system solution for aseptic bioprocessing. With a 750 kDa MWCO and an extended 370 cm2 surface area, it is optimized for the concentration and diafiltration of mid-volume biological samples, including viral vectors, large multi-meric proteins, and nanoparticles.\u003c\/p\u003e\n\n\u003ch3\u003eTechnical Performance and Design\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eAdvanced mPES Membrane:\u003c\/b\u003e The modified Polyethersulfone chemistry provides a hydrophilic, low-fouling surface that ensures high water permeability and excellent recovery of sensitive biomolecules (\u0026gt;95% typical recovery).\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003e750 kDa Selective Barrier:\u003c\/b\u003e Specifically tuned for large-molecule Ultrafiltration, providing high retention of viral particles while effectively clearing smaller host cell proteins and buffer components.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eExtended Surface Area:\u003c\/b\u003e The 65 cm effective length provides 370 cm2 of filtration area, offering higher throughput and shorter processing times for batches up to 5 Liters compared to shorter laboratory modules.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eGamma Irradiated (Sterile):\u003c\/b\u003e Supplied sterile and ready for immediate integration into aseptic flow paths, reducing setup time and the risk of batch contamination.\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eProduct Specifications\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eCatalog Number:\u003c\/b\u003e D06-E750-05-S\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eModule Family:\u003c\/b\u003e MidiKros\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eMWCO:\u003c\/b\u003e 750 kDa\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eSurface Area:\u003c\/b\u003e 370 cm2\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eEffective Length:\u003c\/b\u003e 65 cm\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eFiber ID:\u003c\/b\u003e 0.5 mm\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eConnections:\u003c\/b\u003e Female Luer Lock (FLL) ports for secure, tool-free integration with standard lab-scale TFF tubing sets.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eSterility:\u003c\/b\u003e Gamma Irradiated (Sterile)\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eKey Benefits \u0026amp; Applications\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eViral Vector Processing:\u003c\/b\u003e A premier choice for the concentration and buffer exchange of AAV and Lentiviral vectors in gene therapy research.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eVaccine Development:\u003c\/b\u003e Ideal for the purification of large viral antigens and recombinant protein vaccines at the laboratory scale.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eNanoparticle Clarification:\u003c\/b\u003e Provides a gentle, low-shear environment necessary for the washing and volume reduction of exosomes and lipid nanoparticles.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eScalable Process Development:\u003c\/b\u003e Part of the Spectrum filtration line, ensuring that performance data generated with this MidiKros module is directly applicable to larger MiniKros and KrosFlo production systems.\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003chr\u003e\n\u003cp style=\"margin: 0; font-size: 0.8em;\"\u003e\u003ci\u003eAll product names, logos, and brands are property of their respective owners.\u003c\/i\u003e\u003c\/p\u003e","brand":"Repligen","offers":[{"title":"Default Title","offer_id":44497036214524,"sku":"3822","price":162.94,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0627\/8463\/5132\/files\/repligen-midikros-hollow-fiber-filter-mpes-750-kda-filters-repligen-129453.jpg?v=1778281171","url":"https:\/\/lifesciencestrading.com\/products\/repligen-midikros-hollow-fiber-filter-mpes-750-kda-1","provider":"Life Sciences Trading","version":"1.0","type":"link"}