Sartorius Filter Assembly with Masterflex Tubing 5 Assemblies

Sartorius 5055303PV--LX--C SartoScale 25 Filter Assembly – Sartopure PP3, 1.2 µm

The Sartorius 5055303PV--LX--C is a high-performance, small-scale filtration assembly designed to provide accurate linear scale-up data for large-scale biopharmaceutical processes. This SartoScale 25 unit contains Sartopure PP3 depth filter media, featuring a 1.2 µm nominal retention rating. The PP3 media is constructed from multiple layers of graduated-density polypropylene, offering exceptional dirt-holding capacity and superior protection for sensitive downstream sterile filters or chromatography columns. This specific "LX" assembly comes pre-mounted with Masterflex 96410-17 platinum-cured silicone tubing, making it immediately compatible with L/S series peristaltic pumps. This integrated design minimizes set-up time and reduces the risk of contamination in critical applications such as cell culture clarification, media filtration, and the removal of lipids or colloidal particles from plasma fractions.

Technical Performance and Design

• Sartopure PP3 Depth Media: Utilizes an all-polypropylene construction with a multi-layered, graduated pore structure to ensure maximum throughput and effective retention of heterogeneous contaminants.

• Linear Scale-Up: The SartoScale 25 format provides a 25 cm² filtration area, meticulously designed to mimic the fluid dynamics and performance of full-size Sartopure cartridges.

• Pre-Plumbed Masterflex Tubing: Includes factory-installed 96410-17 platinum-cured silicone tubing, known for its ultra-smooth inner bore, low extractables, and exceptional longevity in peristaltic pump heads.

• Broad Chemical Compatibility: The all-polypropylene filter housing and silicone tubing offer excellent resistance to a wide variety of buffers, acids, bases, and specialized bioprocessing reagents.

Product Specifications

• Catalog Number: 5055303PV--LX--C

• Filter Media: Sartopure PP3 (Polypropylene Depth Filter)

• Retention Rating: 1.2 µm

• Filtration Area: 25 cm² (SartoScale 25)

• Tubing: Masterflex 96410-17 (Platinum-Cured Silicone)

• Connectors: Typically includes hose barb or Luer-lock compatible ends (configuration dependent)

Key Benefits & Applications

• Process Development (R&D): The ideal tool for determining the filterability of new formulations and calculating the required filter area for full-scale production batches.

• Downstream Protection: Efficiently removes large particulates and aggregates, significantly extending the life of more expensive 0.2 µm or 0.1 µm sterilizing-grade filters.

• Clarification of Cell Lysates: Capable of handling high-solids loading, making it suitable for the initial clarification steps in protein and vaccine purification.

• Aseptic Transfer: The pre-assembled, sterile nature of the "LX" unit ensures a secure and clean fluid path for small-volume transfers in cleanroom environments.

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