Sartorius SartoScale 25 Sartopure PP3 1.2 um 12 Filters

Sartorius 5055303PV SartoScale 25 Screening Filter (Sartopure® PP3, 1.2 µm)

The Sartorius 5055303PV is a high-performance, single-use screening device designed for filterability trials and process optimization in biopharmaceutical development. Part of the SartoScale family, this unit features a 25 mm diameter Sartopure® PP3 polypropylene fleece membrane with a 1.2 µm retention rating. Engineered to mimic the performance of full-scale production cartridges, the SartoScale 25 allows for accurate throughput and adsorption studies using minimal product volumes (typically <100 ml). The all-polypropylene construction ensures broad chemical compatibility and an ultra-low extractable profile, making it the ideal tool for the clarification and particle reduction of vaccines, proteins, and cell culture media during the R&D phase.

Technical Performance and Design

• Identical Process Media: Utilizes the exact Sartopure® PP3 depth-loading polypropylene fleece found in industrial-scale Midicaps® and cartridges, ensuring seamless data consistency during scale-up.

• Minimized Hold-up Volume: The optimized internal design features a hold-up volume of less than 1 ml, maximizing the recovery of expensive or limited-quantity pilot batches.

• Standardized Luer Connections: Features a Female Luer Lock inlet and a Male Luer Slip outlet, allowing for easy integration with standard syringes, peristaltic pumps, and automated screening manifolds.

• Integrated Venting Port: Equipped with a dedicated upstream venting port to ensure the entire 4.5 cm² effective filtration area (EFA) is fully utilized and free of air locks.

Product Specifications

• Catalog Number: 5055303PV--LX--C

• Filter Family: Sartopure® PP3 (Polypropylene Fleece)

• Retention Rate: 1.2 µm

• Effective Filtration Area (EFA): 4.5 cm²

• Connectors: Female Luer Lock (Inlet) / Male Luer Slip (Outlet)

• Max Operating Pressure: 5 bar (72.5 psi) @ 20°C; 2 bar (29 psi) @ 80°C

• Sterility: Non-sterile (Fully Autoclavable at 134°C, 2 bar, 30 min)

• Packaging: Sold as a box of 6 units.

Key Benefits & Applications

• Filterability Screening: The essential first step in determining the required filtration area for large-scale production, preventing over-sizing and reducing overall process costs.

• Clarification & Pre-filtration: Ideal for the removal of large particulates and aggregates that could prematurely foul expensive 0.2 µm sterilizing-grade membranes.

• Biopharmaceutical R&D: Frequently used in the development of monoclonal antibodies (mAbs), recombinant proteins, and plasma fractions where low unspecific binding is required.

• Regulatory Compliance: Manufactured in accordance with ISO 9001; all materials meet USP Class VI plastic requirements and are non-fiber releasing per 21 CFR 211.72.

All product names, logos, and brands are property of their respective owners. Sartopure and SartoScale are registered trademarks of Sartorius AG.