Swissci Microplate MRC Maxi Optimization Plate 48 Well 10 ul Pack of 20 Plates

Swissci UVXPO-48LENS MRC Maxi Optimization Plate – 48-Well, 10 µL, UVXPO

The Swissci UVXPO-48LENS is an advanced 48-well microplate designed specifically for macromolecular crystallization and optimization workflows. Utilizing the sitting-drop vapor diffusion technique, this plate provides the ideal geometry for scaling up initial screening hits into large, single crystals suitable for X-ray diffraction. A key innovation of the UVXPO-48LENS is its material construction: the UVXPO polymer. This optically superior material offers ultra-low auto-fluorescence for high-contrast UV imaging, allowing researchers to easily differentiate organic protein crystals from inorganic salt precipitates. Additionally, it exhibits a uniform, zero-background profile when observed under cross-polarized light. Featuring perfectly conical wells that create an illuminating lens effect, robust partition walls for flawless tape sealing, and microscopic numbering for easy navigation, the MRC Maxi is the ultimate platform for demanding structural biology applications.

Technical Performance and Design

• UVXPO Optical Polymer: Engineered to provide maximum transmittance of ultraviolet light for tryptophan fluorescence imaging while remaining completely isotropic to eliminate birefringence under polarized light.

• Lens Effect Geometry: Each sitting-drop well is conically shaped to act as a focal lens, ensuring perfect sample illumination and eliminating optical distortions during manual or automated inspections.

• Easy Crystal Retrieval: The raised, wide design of the sample wells allows researchers to easily introduce a cryo-loop for harvesting without the risk of striking the well walls or damaging delicate crystals.

• Superior Sealing Architecture: Features extra-wide partition walls between the 48 wells, providing a massive, flat surface area for sealing films to adhere to, which prevents edge effects and sample evaporation during extended incubation periods.

Product Specifications

• Catalog Number: UVXPO-48LENS

• Format: 48-Well Sitting-Drop

• Maximum Drop Volume: 10 µL per sample well

• Maximum Reservoir Volume: 200 µL per reagent well

• Material: UVXPO Polymer (UV and Cross-Polarization Compatible)

• Footprint: ANSI/SLAS Standard Microplate

Key Benefits & Applications

• Crystallization Optimization: The increased volume capacities make this the ideal transition plate for moving from nano-liter screening to the micro-liter scale required for structural determination.

• False-Positive Prevention: The UV-compatible polymer allows automated imagers to immediately identify whether a hit is a protein crystal or just salt precipitation, saving valuable beamline time.

• Workflow Versatility: The robust, warp-free footprint is fully compatible with standard robotic pipetting systems and automated crystal imagers, yet remains highly accessible for manual benchtop setups.

• Error-Free Navigation: Integrated micro-numbering (visible only under a microscope) ensures that researchers never lose their orientation while scanning across the grid at high magnifications.

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