{"product_id":"thermo-500-ml-bottle-top-filter-fast-pes-filter-0-2-um","title":"Thermo Scientific Bottle Top Filter 500 ml Rapid Flow 0.2 um PES Case of 12 Filters","description":"\u003ch3\u003eThermo Scientific™ Nalgene™ Rapid-Flow™ Sterile 500 mL Bottle-Top Filters, 0.2 µm PES (566-0020) – Case of 12\u003c\/h3\u003e\n\u003cp\u003eThe Thermo Scientific™ Nalgene™ 566-0020 Bottle-Top Filter is a premium, sterile fluid-handling component engineered for the high-throughput vacuum filtration of cell culture media, serum, buffers, and sensitive biological reagents. Featuring a generous 500 mL upper capacity and a 45 mm neck size, this unit utilizes the proprietary Rapid-Flow™ support plate design paired with an asymmetric polyethersulfone (PES) membrane. This configuration optimizes fluid logistics by delivering exceptionally high flow rates and low clogging tendencies while maintaining a sterile 0.2 micrometer (µm) biological barrier. Supplied as a commercial facility case of 12 individually wrapped filters, this single-use component docks directly onto standard 45 mm thread glass or plastic media storage bottles to support sterile fluid prep loops.\u003c\/p\u003e\n\u003ch3\u003eTechnical Performance \u0026amp; Architecture\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eAsymmetric PES Membrane Matrix: Outfitted with an advanced polyethersulfone membrane that exhibits remarkably low protein binding and low extractable profiles. This preserves the precise nutritional, growth-factor, and chemical balance of premium media recipes and downstream analytical buffers.\u003c\/li\u003e\n\u003cli\u003eProprietary Rapid-Flow™ Geometry: Engineered with a unique internal support plate pattern that distributes vacuum pressure evenly across the entire surface of the PES membrane. This reduces membrane stress and maximizes filtration velocity, significantly cutting down processing time under a biosafety hood.\u003c\/li\u003e\n\u003cli\u003e0.2 µm Sterile Biological Barrier: Certified to provide full retention of common laboratory contaminants such as bacteria and fungi, meeting strict sterilizing-grade filtration guidelines for critical upstream cell culture expansion workflows.\u003c\/li\u003e\n\u003cli\u003eIndividually Wrapped Aseptic Security: Every bottle-top unit is sterilized via validated gamma-irradiation loops and individually sealed in an easy-to-open plastic pouch. This preserves sterile boundaries right up to the moment of thread docking under cleanroom laminar flow hoods.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eProduct Specifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eCatalog Number \/ MPN: 566-0020 (Alternative Ref: 5660020)\u003c\/li\u003e\n\u003cli\u003ePrimary Manufacturer: Thermo Scientific™ (Nalgene™ Filtration Portfolio)\u003c\/li\u003e\n\u003cli\u003eUpper Funnel Volume: 500 mL\u003c\/li\u003e\n\u003cli\u003eMembrane Pore Size: 0.2 µm sterilizing grade\u003c\/li\u003e\n\u003cli\u003eMembrane Diameter Profile: 75 mm nominal diameter\u003c\/li\u003e\n\u003cli\u003eMembrane Material Chemistry: Hydrophilic Polyethersulfone (PES)\u003c\/li\u003e\n\u003cli\u003eThread Neck Size Connection: 45 mm (GL45 standard compatibility)\u003c\/li\u003e\n\u003cli\u003eSterility \u0026amp; Purity Status: Gamma irradiated (Sterile baseline); Certified Non-Pyrogenic, Non-Cytotoxic, and low-extractable\u003c\/li\u003e\n\u003cli\u003ePackaging Configuration: Case of 12 Filters (Individually bagged units nested securely inside a track-coded master warehouse carton)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eKey Benefits \u0026amp; Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eUpstream Mammalian Media Preparation: The premier choice for fast sterilization of fragile base media, fetal bovine serum (FBS) blends, antibiotics, and vitamin supplements where high protein recovery is paramount.\u003c\/li\u003e\n\u003cli\u003eLarge-Volume Analytical Buffer Clarification: Provides a fast, clean path for filtering complex salt matrices, mobile phases, and HPLC buffers without leaching trace chemical plasticizers into the analytical line.\u003c\/li\u003e\n\u003cli\u003eErgonomic and Safe Vacuum Hookups: Features an integrated, universal quick-connect vacuum tubing adapter that ensures a stable, leak-proof line connection, reducing benchtop clutter and accidental tipover risks.\u003c\/li\u003e\n\u003cli\u003e**CGMP-Compliant Quality Auditing:** Every individual filter body is clearly printed with the catalog number, manufacturing lot code, membrane material, and pore size specification to ensure seamless facility traceability.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eExpiration Date 02\/06\/28\u003c\/p\u003e\n\u003chr\u003e\n\u003cp\u003e\u003csmall\u003eThermo Scientific™, Nalgene™, and Rapid-Flow™ are registered commercial trademarks of Thermo Fisher Scientific Inc. Catalog number 566-0020 specifies the 500 mL funnel size with a 45 mm neck and 0.2 µm PES membrane. For filtering aggressive organic solvents or acids, or for matching with alternative 33 mm thread storage systems, alternative nylon, CA, or specialized PTFE membrane configurations must be cross-referenced within the logistics hub.\u003c\/small\u003e\u003c\/p\u003e","brand":"Thermo Scientific","offers":[{"title":"Default Title","offer_id":45898737713404,"sku":"3769","price":142.5,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0627\/8463\/5132\/files\/IMG_4409_Shopify1024.jpg?v=1782848157","url":"https:\/\/lifesciencestrading.com\/products\/thermo-500-ml-bottle-top-filter-fast-pes-filter-0-2-um","provider":"Life Sciences Trading","version":"1.0","type":"link"}