Thermo Scientific Centrifuge Tube 1.5 ml Snap Cap Low Retention Polypropylene 10 Packs with 500 Tubes Each

Thermo Scientific™ MBP Low-Retention Microcentrifuge Tubes, 1.5 mL Snap Cap (3451) – Case of 5,000 Tubes

The Thermo Scientific™ 3451 is a high-purity molecular biology microcentrifuge tube engineered for absolute sample recovery and structural integrity during high-velocity thermal and mechanical processing. Fabricated from premium, clear virgin polypropylene, these 1.5 mL tubes feature a specialized low-retention inner surface modification that prevents viscous liquids and costly reagents from binding to the walls. Supplied as a bulk facility package of 10 packs containing 500 tubes each (5,000 total tubes), this flat-top snap cap model includes crisp molded graduation increments and an external frosted writing window, optimizing sample identification and traceability for demanding diagnostic assays.

Technical Performance & Design

• **Hydrophobic Low-Retention Surface:** Modified at the molecular level without the use of secondary lubricants, silicone coatings, or fluid additives. This completely chemical-free treatment ensures maximum recovery of proteins, enzymes, nucleic acids, and genomic masters without risking downstream assay interference.
• **Secure Leak-Proof Snap Cap:** Outfitted with a precision-molded, heavy-duty flat-top snap lid that clicks tightly into the internal collar bevel. This seal prevents evaporation, resists accidental pop-opens during intensive thermal boiling or water bath incubations, and maintains structural tightness.
• **High-Velocity RCF Performance:** Structural walls are reinforced with a uniform thickness profile to easily withstand mechanical gravitation stresses up to $26,000 \times \text{g}$, keeping tubes intact during high-speed clarification loops inside standard microcentrifuges.
• **Strict Cleanroom Certification:** Manufactured and packaged under automated cleanroom controls to enforce biochemical purity. Every lot is certified free of detectable RNase, DNase, human DNA, ATP, genomic nucleic acids, and bacterial pyrogens.

Product Specifications

• **Model Number / SKU:** 3451 (MBP / Thermo Scientific™ Specialty Tubes)
• **Primary Manufacturer:** Thermo Fisher Scientific / Molecular BioProducts (MBP)
• **Maximum Volumetric Capacity:** 1.5 mL (Standard conical tube profile)
• **Surface Treatment Class:** High-Hydrophobicity Low-Retention Polymer Matrix
• **Cap / Lid Configuration:** Integrated Flat-Top Snap Cap (Pierceable)
• **Centrifugation Tolerance:** Rated up to $26,000 \times \text{g}$ Maximum RCF
• **Visual Layout Markers:** Molded vertical graduation lines with an external frosted matte marking area for lab markers
• **Purity Level Verification:** Certified DNase-free, RNase-free, Pyrogen-free, ATP-free, and Nucleic Acid-free
• **Material Properties:** Clear, premium autoclavable virgin polypropylene
• **Packaging Configuration:** Bulk Case of 5,000 Tubes (Packaged as 10 durable bags containing 500 loose tubes each)

Key Benefits & Applications

• **Quantitative PCR and Next-Gen Sequencing (NGS):** Crucial for staging expensive master mixes, enzyme solutions, primer pairs, and low-concentration cDNA fragments, guaranteeing that no vital nucleic acids bind to the plastic matrix.
• **Viscous Liquid Handling and Aliquoting:** Ideal for dispensing glycerol stocks, detergents (Triton X-100, Tween-20), protein suspensions, and dense restriction enzymes where residual droplet hang-up can skew pipetting precision.
• **Proteomic Extraction and Storage:** Highly recommended for isolating low-abundance primary cell proteins or peptide fragments, keeping structural binding loss to an absolute minimum during processing.
• **High-Speed Diagnostic Clarification:** Built to run smoothly inside microcentrifuge rotor blocks, allowing for swift pelleting of cellular lysates, blood fragments, or precipitates without mechanical stress cracks.

Thermo Scientific™ and Molecular BioProducts (MBP) are registered commercial trademarks of Thermo Fisher Scientific Inc. SKU 3451 specifies the clear 1.5 mL low-retention model with a flat snap cap. For high-temperature incubation loops prone to severe internal pressure spikes, alternative Specialized Safelock or threaded screw-cap microcentrifuge configurations should be specified instead.