{"product_id":"thermo-scientific-bottletop-filter-1000-ml-rapid-flow-0-45-um-pes","title":"Thermo Scientific Bottletop Filter 1000 ml Rapid Flow 0.45 um PES Case of 12","description":"\u003ch3\u003eThermo Scientific Nalgene 167-0045 1000 ml Rapid-Flow™ Bottle-Top Filter (0.45 µm PES)\u003c\/h3\u003e\n\u003cp\u003eThe Thermo Scientific Nalgene 167-0045 is a 1-liter sterile bottle-top filtration unit designed for the rapid clarification of large-volume laboratory reagents, buffers, and aqueous solutions. Featuring the proprietary Rapid-Flow™ support column design, this unit maximizes filtration speed and throughput while maintaining high structural integrity under vacuum. The 0.45 µm Polyethersulfone (PES) membrane provides superior flow rates and exceptionally low protein binding, ensuring that critical solutes are not lost during the filtration process. This filter is designed to screw directly onto standard glass or plastic media bottles with a 45 mm (GL45) neck finish, providing a secure, leak-proof aseptic transfer path.\u003c\/p\u003e\n\n\u003ch3\u003eTechnical Performance and Design\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eRapid-Flow™ Support Plate:\u003c\/b\u003e The unique internal geometry provides a uniform support surface for the membrane, reducing turbulence and allowing for faster filtration times compared to traditional support designs.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eHigh-Flux PES Membrane:\u003c\/b\u003e The 0.45 µm Polyethersulfone membrane is naturally hydrophilic and contains no wetting agents, offering a high flow rate for aqueous solutions and superior chemical resistance.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eLow Protein Binding:\u003c\/b\u003e Specifically engineered for the filtration of protein-rich solutions, such as serum-supplemented media and monoclonal antibody buffers, ensuring minimal loss of high-value biological analytes.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eSecure GL45 Interface:\u003c\/b\u003e The 45 mm thread size ensures universal compatibility with standard laboratory media bottles, including Nalgene, Schott, and Corning brands, creating a closed-system environment during filtration.\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eProduct Specifications\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eCatalog Number:\u003c\/b\u003e 167-0045\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eVolume Capacity:\u003c\/b\u003e 1000 ml\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eMembrane Type:\u003c\/b\u003e Polyethersulfone (PES)\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003ePore Size:\u003c\/b\u003e 0.45 µm (Clarification Grade)\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eNeck Size:\u003c\/b\u003e 45 mm (GL45)\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eMembrane Diameter:\u003c\/b\u003e 90 mm\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eSterility:\u003c\/b\u003e Sterile (Gamma Irradiated); Non-pyrogenic; Non-cytotoxic\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003ePackaging:\u003c\/b\u003e 12 Units per Case\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eKey Benefits \u0026amp; Applications\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eBuffer \u0026amp; Reagent Clarification:\u003c\/b\u003e Optimized for the removal of particulates and large colloidal matter from laboratory buffers, salt solutions, and mobile phases.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eCell Culture Support:\u003c\/b\u003e Ideal for clarifying aqueous solutions that will be subsequent sterile-filtered (0.22 µm), extending the life of the final sterilizing membrane.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eHigh Throughput Workflows:\u003c\/b\u003e The large 90 mm membrane diameter and Rapid-Flow technology make this the preferred choice for processing 1-liter batches quickly without membrane clogging.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eCertified Biological Safety:\u003c\/b\u003e Each lot is tested for sterility and is certified non-cytotoxic, ensuring it will not interfere with sensitive cell-based assays or pharmaceutical development.\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003chr\u003e\n\u003cp style=\"margin: 0; font-size: 0.8em;\"\u003e\u003ci\u003eAll product names, logos, and brands are property of their respective owners. Nalgene and Rapid-Flow are trademarks of Thermo Fisher Scientific.\u003c\/i\u003e\u003c\/p\u003e","brand":"Thermo Scientific","offers":[{"title":"Default Title","offer_id":44498163040508,"sku":"4292","price":130.62,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0627\/8463\/5132\/files\/thermo-scientific-bottletop-filter-1000-ml-rapid-flow-045-um-pes-case-of-12-filters-thermo-scientific-781992.jpg?v=1764490258","url":"https:\/\/lifesciencestrading.com\/products\/thermo-scientific-bottletop-filter-1000-ml-rapid-flow-0-45-um-pes","provider":"Life Sciences Trading","version":"1.0","type":"link"}