{"product_id":"thermo-scientific-carboy-aseptic-closure-with-1-4-in-and-two-1-8-in-id-ports","title":"Thermo Scientific Carboy Aseptic Closure with 1\/4 in. and Two 1\/8 in. ID Ports","description":"\u003ch3\u003eThermo Scientific Nalgene Aseptic Closure (83B Closure, Catalog 2135-3803)\u003c\/h3\u003e\n\u003cp\u003eThe Thermo Scientific Nalgene 2135-3803 is a specialized cap assembly engineered to transform standard Nalgene carboys into high-integrity, closed fluid transfer systems. Designed specifically for vessels with an 83B (83 mm) neck finish—typically ranging from 10L to 50L capacities—this closure facilitates the aseptic filling, venting, and dispensing of critical fluids without environmental exposure. The assembly features a precision-engineered three-port configuration that eliminates the contamination risks and leakage common with manually drilled caps. By allowing the entire carboy and tubing manifold to be sterilized as a single unit, the 2135-3803 significantly streamlines both upstream and downstream bioprocessing workflows.\u003c\/p\u003e\n\n\u003ch3\u003eTechnical Performance and Design\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eSecure 83B Interface:\u003c\/b\u003e Designed for large-format carboys, the high-torque polypropylene (PP) screw cap provides a robust mechanical seal capable of withstanding the rigors of pharmaceutical transport and storage.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003ePlatinum-Cured Silicone Gasket:\u003c\/b\u003e Includes a high-purity silicone gasket that ensures a leak-proof seal even during the thermal expansion and contraction cycles of autoclaving, preventing bypass contamination.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eIntegrated Tri-Port Layout:\u003c\/b\u003e Features a versatile port configuration including one 1\/4-inch ID port for primary liquid transfer and two 1\/8-inch ID ports optimized for venting, sampling, or reagent additions.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eContamination-Free Construction:\u003c\/b\u003e Precision-molded ports eliminate the burrs and irregularities associated with manual drilling, ensuring a perfectly circular path for tubing or connectors to maintain a sterile barrier.\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eProduct Specifications\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eCatalog Number:\u003c\/b\u003e 2135-3803\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eClosure Size:\u003c\/b\u003e 83B (83 mm)\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003ePrimary Port:\u003c\/b\u003e 1\/4-inch (6.4 mm) ID\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eSecondary Ports:\u003c\/b\u003e Two 1\/8-inch (3.2 mm) ID\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eMaterials:\u003c\/b\u003e Polypropylene (Cap), Platinum-Cured Silicone (Gasket)\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eSterility\/Sanitation:\u003c\/b\u003e Non-sterile; Fully Autoclavable (121°C)\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eRegulatory:\u003c\/b\u003e Manufactured from USP Class VI compliant materials; Non-cytotoxic.\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eKey Benefits \u0026amp; Applications\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eBulk Liquid Transfer:\u003c\/b\u003e The 1\/4\" port is ideal for connecting dip tubes to enable the complete, aseptic extraction of media or buffers from 20L or 50L carboys.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eSterile Venting \u0026amp; Pressure Equalization:\u003c\/b\u003e Dedicated 1\/8\" ports allow for the permanent attachment of 50mm PTFE vent filters, ensuring safe pressure equilibration during autoclaving and fluid dispense.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eLarge-Scale Bioprocessing:\u003c\/b\u003e Specifically designed for large-volume Nalgene carboys used in vaccine manufacturing, cell culture scale-up, and bulk reagent storage.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eModular Versatility:\u003c\/b\u003e The three-port design supports complex manifold setups, allowing researchers to create customized, validated fluid paths for diafiltration or harvest collection.\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003chr\u003e\n\u003cp style=\"margin: 0; font-size: 0.8em;\"\u003e\u003ci\u003eAll product names, logos, and brands are property of their respective owners. Nalgene is a trademark of Thermo Fisher Scientific.\u003c\/i\u003e\u003c\/p\u003e","brand":"Thermo Scientific","offers":[{"title":"Default Title","offer_id":44497101127932,"sku":"4022","price":83.6,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0627\/8463\/5132\/files\/thermo-scientific-carboy-aseptic-closure-with-14-in-and-two-18-in-id-ports-bottles-thermo-scientific-205443.jpg?v=1778282176","url":"https:\/\/lifesciencestrading.com\/products\/thermo-scientific-carboy-aseptic-closure-with-1-4-in-and-two-1-8-in-id-ports","provider":"Life Sciences Trading","version":"1.0","type":"link"}