Thermo Scientific Cryogenic Vials 5 mL PP Case of 250 Vials

Thermo Scientific Nalgene 5000-0050 5 ml Cryogenic Vial (External Thread, Sterile)

The Thermo Scientific Nalgene 5000-0050 is a 5 ml high-capacity cryogenic vial engineered for the secure, long-term storage of biological samples, genomic material, and cell cultures. Manufactured from medical-grade, high-clarity polypropylene, these vials are designed to withstand extreme temperatures ranging from -196°C (vapor phase LN2) to +120°C. The external thread design reduces the risk of sample contamination by ensuring that the sealing surfaces are not exposed during cap removal. Each vial features a self-standing skirted base that interlocks with Nalgene cryogenic racks for efficient one-handed operation. Certified sterile, non-cytotoxic, and non-pyrogenic, these vials are the industry standard for biobanking and sensitive laboratory research.

Technical Performance and Design

• External Thread Architecture: The cap threads onto the outside of the vial, preventing the "wicking" of liquids and significantly reducing the risk of contamination compared to internal thread designs. This is ideal for maintaining aseptic technique in the laminar flow hood.

• Cryogenic Temperature Resilience: Validated for use in mechanical freezers and the vapor phase of liquid nitrogen (LN2). Note: For safety, vials should not be submerged in the liquid phase of nitrogen unless sealed in Nunc CryoFlex™ tubing.

• Self-Standing (Skirted) Base: The flat, skirted bottom allows the vial to stand independently on the benchtop. The star-style base interlocks with the wells of Nalgene cryogenic vial holders, permitting easy one-handed opening and closing.

• Enhanced Sample Identification: Each vial is printed with large, bold graduations and a white marking area that is resistant to smudge and common lab solvents, ensuring reliable sample tracking over decades of storage.

Product Specifications

• Catalog Number: 5000-0050

• Volume Capacity: 5.0 ml

• Material: Polypropylene (Vial) / HDPE (Closure)

• Dimensions: 13.5 mm (OD) x 92 mm (Height)

• Thread Type: External Thread with Screw Cap

• Sterility: Sterile (SAL 10⁻⁶); Certified DNAse/RNAse-free; Non-pyrogenic; Non-cytotoxic.

• Packaging: 10 Vials per Pack / 250 Vials per Case

Key Benefits & Applications

• Biobanking & Genomic Storage: The high 5 ml capacity is perfect for large-volume tissue samples, bulk serum, or high-density cell stocks that require long-term stability.

• Aseptic Handling: The deep-skirted cap allows for secure handling without touching the vial opening, preserving the integrity of sensitive cultures and template DNA.

• Dangerous Goods Compliant: Meets the IATA/ICAO regulations for the transport of infectious and diagnostic specimens by air when used as a primary receptacle.

• Leak-Proof Closure: The basic design uses a specialized sealing ring in conjunction with precision-molded threads to ensure a liquid-tight seal without the need for an O-ring, which can be a source of contamination.

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