Thermo Scientific Dialysis Cassette Slide-A-Lyzer 7 K MWCO 0.5 ml 12 Cassettes

The Thermo Scientific 66373 Slide-A-Lyzer Dialysis Cassette is a specialized laboratory tool designed for the efficient dialysis of small-volume biological samples. This cassette has a sample capacity of 0.5 ml, making it ideal for processing valuable or limited-quantity samples where minimizing volume loss is critical. The convenient cassette design replaces traditional dialysis tubing, offering a rigid, easy-to-handle format that simplifies loading and retrieval.

A key feature of this cassette is its 7 K (7,000 Dalton) molecular weight cutoff (MWCO). This specification means the semipermeable membrane allows molecules smaller than 7 kDa (such as salts, reducing agents, and small metabolites) to pass through into the dialysis buffer, while efficiently retaining larger macromolecules, such as proteins and nucleic acids, inside the cassette. The membrane is typically made of low-binding regenerated cellulose, ensuring maximum sample recovery.

The design incorporates a leak-proof gasket and allows for sample loading and removal via a syringe needle through a self-sealing port. This Thermo Scientific Slide-A-Lyzer cassette is an essential tool in biochemistry and molecular biology for applications such as desalting, buffer exchange, and the removal of low-molecular-weight contaminants from sensitive biological samples.