Thermo Scientific Erlenmeyer Flask 2800 ml Baffled PETG Case of 4 Flasks

Thermo Scientific Nalgene 4116-2800 Erlenmeyer Flask – 2800 mL, Baffled Bottom, PETG

The Thermo Scientific Nalgene 4116-2800 is a high-capacity 2.8L Fernbach-style Erlenmeyer flask designed for large-scale suspension cell culture and aerobic fermentation. Constructed from high-clarity, medical-grade PETG, this flask provides the optical transparency of glass with the safety and impact resistance of high-performance plastic. The flask is engineered with a baffled bottom, which promotes vigorous agitation and increases the surface-to-volume ratio during shaking to optimize gas exchange. Supplied sterile and non-pyrogenic, the 4116-2800 is a reliable, single-use alternative to glass flasks, eliminating the need for time-consuming cleaning and validation while reducing the risk of cross-contamination in biopharmaceutical production.

Technical Performance and Design

• Triple-Baffled Bottom: The molded-in baffles disrupt the laminar flow of the media during orbital shaking, creating a turbulent environment that significantly enhances oxygenation for high-demand aerobic cultures.

• High-Clarity PETG: Manufactured from USP Class VI polyethylene terephthalate glycol, offering excellent visibility for monitoring cell growth and media color changes without the breakage risk of borosilicate glass.

• Vented Screw Closure: Includes a 70 mm vented cap with a 0.2 µm hydrophobic membrane, allowing for continuous, sterile gas exchange while maintaining a secure barrier against airborne contaminants.

• Sterile & Disposable: Gamma irradiated to a Sterility Assurance Level (SAL) of 10⁻⁶, these flasks are designed for single-use "plug and play" workflows, saving on labor and energy costs associated with autoclaving.

Product Specifications

• Catalog Number: 4116-2800

• Capacity: 2800 mL (2.8 Liters)

• Material: PETG (USP Class VI)

• Bottom Shape: Baffled

• Closure Size: 70 mm

• Sterility: Sterile (Gamma Irradiated)

• Certifications: Non-pyrogenic, Non-cytotoxic, and Animal Derived Component-Free (ADCF).

Key Benefits & Applications

• Large-Scale Protein Expression: Ideal for the cultivation of E. coli, yeast, and other microbial strains used in the production of recombinant proteins and enzymes.

• Seed Train Expansion: Provides the high oxygen transfer rates necessary to quickly scale up cell densities before inoculation into large-scale bioreactors.

• Laboratory Safety: The shatterproof PETG construction protects personnel and high-value research by preventing the catastrophic spills and injuries common with large glass flasks.

• Standardized Footprint: Despite the large volume, the base is designed to fit standard large-capacity orbital shaker clamps, ensuring easy integration into existing laboratory equipment.

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