Thermo Scientific Flask with Vented Closure 500 mL Case of 12 Flasks

Thermo Scientific Nalgene 500 ml Polycarbonate Flask with Vent Cap (4115-0500)

The Thermo Scientific Nalgene 4115-0500 is a high-performance 500 ml Erlenmeyer flask designed for sterile culture applications, reagent storage, and media preparation. Manufactured from medical-grade, optically clear polycarbonate, this flask offers the transparency of glass with the impact resistance and safety of a high-strength polymer. The unit is equipped with a blue vented closure featuring an integrated 0.2 µm hydrophobic PTFE membrane, which allows for continuous, sterile gas exchange while providing a secure barrier against airborne contaminants and preventing liquid leakage. With its plain-bottom design and molded-in graduations, the 4115-0500 is the industry standard for researchers performing suspension cell culture, chemical mixing, and aseptic liquid handling in shakers and incubators.

Technical Performance and Design

• Hydrophobic Vented Closure: The 38 mm blue vent cap ensures consistent O2 and CO2 exchange for aerobic cultures while maintaining a sterile internal environment even during vigorous shaking.

• Plain-Bottom Geometry: The flat, non-baffled base is optimized for standard mixing applications and applications where excessive turbulence is not desired, ensuring a predictable fluid path during orbital shaking.

• Shatter-Proof Security: Constructed from impact-resistant polycarbonate, this flask eliminates the hazards associated with glass breakage in the laboratory, particularly during high-speed centrifugation or mechanical agitation.

• Optical Clarity & Graduations: Provides a crystal-clear view of sample levels and culture turbidity, supported by permanent, molded-in graduations that provide accurate volume assessment at a glance.

Product Specifications

• Catalog Number: 4115-0500

• Capacity: 500 ml

• Material: Polycarbonate (Flask); Polypropylene (Cap)

• Cap Style: 38-430 Vented Closure (0.2 µm PTFE Membrane)

• Bottom Style: Plain (Non-Baffled)

• Sterility: Sterile (Gamma Irradiated to SAL 10^-6)

• Purity: Certified Non-Pyrogenic and Non-Cytotoxic.

• Graduations: Molded-in at 50 ml increments.

Key Benefits & Applications

• Sterile Shaker Culture: The primary choice for culturing mammalian, insect, and microbial cells where aseptic aeration is required without the high shear force of baffles.

• Media & Buffer Preparation: Excellent for the sterile filtration and storage of aqueous solutions, ensuring long-term purity and stability.

• Suspension Scale-Up: Provides a reliable, single-use platform for researchers transitioning from smaller flasks to larger production volumes in orbital shakers.

• Lab Safety: Lightweight and durable, these flasks are preferred for high-traffic lab environments and for use in automated platform stackers.

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