{"product_id":"thermo-scientific-pierce-protein-precipitation-plate-96-well-0-2-um-hydrophobic","title":"Thermo Scientific Pierce Protein Precipitation Microplate 96 Well 8 Plates","description":"\u003ch3\u003eThermo Scientific Pierce Protein Precipitation Plates - 96-Well Format, 2 mL Well Volume, Graded Hydrophobic Frit, 0.2 Micron Cutoff Membrane (MPN: 90037)\u003c\/h3\u003e\n\u003cp\u003eThe Thermo Scientific 90037 (part of the Pierce Biotechnology product family) is a high-performance 96-well protein precipitation microplate engineered for rapid, automated, or manual extraction and clarification of small molecule analytes from complex biological fluids like plasma, serum, and whole blood. Featuring a spacious 2 mL well capacity that accommodates serum sample volumes ranging from 15 to 400 microliters, these solvent-inert polypropylene plates utilize a specialized \"protein crash\" workflow technique. Built with a leach-free, graded hydrophobic frit system, the plate retains organic solvents like acetonitrile or methanol without dripping during critical automated platform shaking loops, then allows purified filtrates to be drawn down while trapping precipitated protein aggregates behind a clean 0.2 micron cutoff membrane.\u003c\/p\u003e\n\n\u003ch3\u003eTechnical Performance and Design\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eDrip-Free Hydrophobic Frit Design:\u003c\/b\u003e Pre-packed with a non-wetting, graded hydrophobic frit matrix. This specialized barrier completely retains aggressive organic solvents (including 100 percent acetonitrile or methanol) for up to four hours without leaking or dripping, allowing for long on-plate mixing and precipitation routines.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eAnti-Clogging 0.2 Micron Cutoff Layer:\u003c\/b\u003e Outfitted with a graded filter system featuring decreasing pore sizes that lead down to a tight 0.2 micron cutoff membrane. This layout locks away dense, sticky precipitated protein shards and macromolecular debris without plugging up, guaranteeing high eluate filtration flow and analyte recovery.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eOversized 2 mL Processing Cavities:\u003c\/b\u003e Well dimensions support a generous 2 mL volume profile, which is highly optimized for executing standard 3:1 or 4:1 solvent-to-serum precipitation ratios without well overflowing or side-wall fluid aerosol talk during intensive platform mixing passes.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eMulti-System Elution Flexibility:\u003c\/b\u003e The structural bottom profile of the plate deck is engineered to release clean filtrates under uniform mechanical forces, operating with standard laboratory vacuum manifolds, automated positive pressure modules, or standard multiwell plate centrifuge buckets.\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eProduct Specifications\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eCatalog Number \/ MPN:\u003c\/b\u003e 90037 (Commonly cross-listed as PI90037)\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eManufacturer \/ Brand:\u003c\/b\u003e Thermo Scientific \/ Pierce Protein lines\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eFormat Layout:\u003c\/b\u003e Standard 96-Well Grid (8 x 12 Array Arrangement)\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eTotal Well Capacity:\u003c\/b\u003e 2.0 mL total volume per well\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eRecommended Sample Input:\u003c\/b\u003e 15 to 400 microliters of serum\/plasma per well\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eFilter Membrane Profile:\u003c\/b\u003e Graded Hydrophobic Frit terminating at a 0.2 micron microfiltration membrane\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eMaterial Composition:\u003c\/b\u003e Solvent-Inert Medical-Grade Polypropylene (PP)\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eSterility \/ Process State:\u003c\/b\u003e Non-Sterile (Optimized for biofluid small molecule isolation and HPLC sample cleanup tasks)\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eIncluded Accessories:\u003c\/b\u003e Every factory kit package ships complete with specialized plate sealing covers\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eKey Benefits and Applications\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eLC-MS and HPLC Sample Prep:\u003c\/b\u003e The industry-standard microplate tool used to strip out background protein interferences from blood derivatives, preparing clean small-molecule extracts for analytical mass spectrometry injections in 10 to 30 minutes.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003ePharmacokinetic and RED Assay Cleanup:\u003c\/b\u003e Highly recommended for downstream sample harvesting from Rapid Equilibrium Dialysis (RED) devices, supporting essential plasma-protein binding (PPB) evaluations during drug candidate profiling phases.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eHigh-Throughput Automation Workflows:\u003c\/b\u003e Conforms strictly to ANSI\/SLAS microplate footprints, allowing automated liquid handling arms, plate shakers, and robotic vacuum stations to grip and process plates without custom adjustments.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eZero Extractable Sample Protection:\u003c\/b\u003e Constructed using leach-free polymer materials, ensuring no baseline plasticizer compounds or slip-agents bleed into the eluted samples to disrupt high-sensitivity chromatography signals.\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003chr\u003e\n\u003cp style=\"margin: 0; font-size: 0.8em;\"\u003e\u003ci\u003eAll product names, logos, and brands are property of their respective owners.\u003c\/i\u003e\u003c\/p\u003e","brand":"Thermo Scientific","offers":[{"title":"Default Title","offer_id":46139298021628,"sku":"6552","price":182.88,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0627\/8463\/5132\/files\/thermo-scientific-pierce-protein-precipitation-microplate-96-well-8-plates-lcmsgc-thermo-scientific-386388.jpg?v=1721247961","url":"https:\/\/lifesciencestrading.com\/products\/thermo-scientific-pierce-protein-precipitation-plate-96-well-0-2-um-hydrophobic","provider":"Life Sciences Trading","version":"1.0","type":"link"}