Thermo Scientific Slide-A-Lyzer Cassette G2 20K MWCO 70 ml Pack of 6

Thermo Scientific™ 87738 Slide-A-Lyzer™ G2 Dialysis Cassette (70 ml, 20K MWCO)

The Thermo Scientific™ 87738 is a high-performance, second-generation (G2) dialysis cassette designed for the rapid and secure buffer exchange, desalting, and concentration of biological samples. Featuring a 20,000 MWCO (Molecular Weight Cut-Off) regenerated cellulose membrane, this cassette is optimized for the purification of proteins and macromolecules with a volume range of 10 to 70 ml. The G2 design eliminates the risks associated with traditional dialysis tubing, such as leaks and sample loss, by utilizing a rigid, leak-proof housing. With its high surface-area-to-volume ratio, the 87738 ensures maximum dialysis efficiency, allowing researchers to achieve high-purity results in a fraction of the time required by conventional methods.

Technical Performance and Design

• Premium 20K MWCO Membrane: Constructed from high-purity regenerated cellulose, providing excellent chemical compatibility and low non-specific protein binding for maximum sample recovery.

• Large Volume Capacity: Specifically engineered to handle up to 70 ml of sample, bridging the gap between bench-scale research and pilot-scale production.

• Innovative G2 Loading System: Features a specialized port design that allows for easy sample loading and retrieval using a serological pipette or syringe, significantly reducing the risk of membrane puncture.

• Self-Floating Design: The cassette is engineered to be air-buoyant, ensuring it remains upright and floating during the dialysis process for optimal membrane exposure and convenience.

Product Specifications

• Catalog Number: 87738

• Membrane Type: Regenerated Cellulose

• MWCO: 20,000 Daltons (20K)

• Sample Volume Range: 10 ml – 70 ml

• Cassette Format: G2 (Second Generation)

• Quantity: Sold individually or in packs (please verify physical unit).

Key Benefits & Applications

• Protein Desalting & Buffer Exchange: The gold standard for removing salts, urea, or detergents from protein preparations prior to downstream analysis or storage.

• Sample Concentration: Can be used in conjunction with hygroscopic polymers (like PEG) to gently concentrate dilute biological samples.

• Biopharmaceutical Scale-Up: Ideal for researchers moving from small analytical samples to larger volumes required for structural biology or functional assays.

• Reduced Processing Time: The high-surface-area design facilitates faster diffusion rates, typically completing dialysis 2-4 times faster than traditional tubing.

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