Thermo Scientific Slide-A-Lyzer Dialysis Cassette G2 15 ml 20 kDa 8 Cassettes

Thermo Scientific 87736 Slide-A-Lyzer G2 Dialysis Cassette (15 ml, 20K MWCO)

The Thermo Scientific 87736 Slide-A-Lyzer G2 is a second-generation dialysis device engineered for the rapid and secure buffer exchange, desalting, and contaminant removal of 5 ml to 15 ml biological samples. Featuring a 20,000 MWCO (Molecular Weight Cut-Off) low-binding regenerated cellulose membrane, this cassette ensures maximum sample recovery (>95%) while maintaining high purity. The G2 design is unique for its "needle-free" accessibility, allowing researchers to load and recover samples using standard serological pipettes or tips through a dedicated port. Additionally, the integrated air chamber provides self-floating buoyancy, keeping the cassette upright and suspended during the dialysis process without the need for external float buoys.

Technical Performance and Design

• Needle-Free Pipette Access: The G2 series features a unique sample port that accommodates pipettes, eliminating the safety risks and sample loss associated with traditional syringe-and-needle loading methods.

• Self-Floating Air Chamber: An integrated air pocket at the top of the frame ensures the cassette remains buoyant and vertically oriented in the dialysis buffer, optimizing the surface-area-to-volume ratio for faster kinetics.

• Low-Binding Regenerated Cellulose: The high-quality membrane minimizes non-specific binding of proteins and nucleic acids, ensuring high yields even with low-concentration samples.

• Hermetically Sealed Chamber: Unlike traditional dialysis tubing that relies on manual clips, the G2 cassette features a factory-welded membrane and a leak-proof screw cap to prevent sample leakage or dilution.

Product Specifications

• Catalog Number: 87736

• Sample Volume Range: 5.0 ml – 15.0 ml

• MWCO (Cut-off): 20 kDa

• Membrane Material: Regenerated Cellulose

• Frame Material: ABS Plastic (White/Clear)

• Sterility: Non-Sterile (Clean-room manufactured)

• Packaging: 8 Cassettes per Pack

Key Benefits & Applications

• Buffer Exchange & Desalting: Highly efficient for removing salts, urea, and other low-molecular-weight contaminants from protein or antibody preparations.

• Biopharmaceutical Research: Ideal for cleaning up labeled proteins or preparing samples for mass spectrometry where high recovery and purity are non-negotiable.

• Enhanced Lab Safety: The pipette-accessible port allows for one-handed operation and reduces the risk of sharps-related injuries in the lab.

• High Surface Area: The flat-panel design provides a significantly higher surface-area-to-sample-volume ratio than conventional tubing, reducing dialysis time from days to hours.

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