WaterSep Hollow Fiber Filter Cartridge Discover12 Green Sealed Filter

WaterSep SU 920 10DIS12 LL Discover12 Green Hollow Fiber Filter – 0.2 µm, 52 cm²

The WaterSep BioSeparations SU 920 10DIS12 LL is a high-performance hollow fiber filter cartridge designed for small-scale tangential flow filtration (TFF) and bioprocess development. Belonging to the single-use "Green Line," this Discover12 module is gamma-irradiated, completely glycerin-free, and ready to use without the extensive pre-flushing required by traditional membranes. Featuring a highly hydrophilic modified Polyethersulfone (m-PES) membrane with a 0.2 µm pore size and a 1.0 mm fiber inner diameter, it is specifically optimized for cell harvesting, clarification of cell culture broths, and microfiltration of delicate biologicals. With a 52 cm² effective filtration area and standard Luer Lock connections, the Discover12 provides excellent linear scalability and seamless integration into benchtop R&D workflows.

Technical Performance and Design

• Green Line Ready-to-Use Technology: Manufactured without humectants (glycerin-free), this cartridge features 80x fewer extractables than standard membranes, eliminating time-consuming cleaning validation and extensive pre-rinsing.

• Low-Binding m-PES Membrane: The modified polyethersulfone chemistry provides exceptionally low non-specific protein binding, ensuring maximum product recovery and high, consistent flux rates during microfiltration.

• Low-Shear Hollow Fiber Geometry: The open-channel, 1.0 mm ID hollow fibers create a gentle, low-shear fluid path that is essential for processing fragile mammalian cells (like CHO cells), yeast, and bacteria without causing shear-induced lysis.

• Direct Scalability: The Discover12 replicates the path length and fluid dynamics of larger pilot and production-scale WaterSep cartridges, allowing for highly accurate scale-up calculations from lab to manufacturing.

Product Specifications

• Catalog Number: SU 920 10DIS12 LL

• Product Line: Discover12 (Green Line)

• Pore Size: 0.2 µm

• Membrane Material: Modified Polyethersulfone (m-PES)

• Fiber Inner Diameter (ID): 1.0 mm

• Effective Filtration Area: 52 cm²

• Connections: Luer Lock (LL)

• Sterility: Single-Use, Pre-sterilized (Gamma Irradiated)

Key Benefits & Applications

• Cell Harvest & Clarification: The 0.2 µm pore size is the industry standard for removing intact cells, cell debris, and large particulates from fermentation broths and cell culture supernatants.

• Time and Cost Savings: As a true single-use, pre-sterilized module, it completely bypasses the need for clean-in-place (CIP) protocols, saving hours of preparation and validation time.

• Benchtop TFF Integration: Standard Luer Lock ports allow for effortless, plug-and-play connection to laboratory syringe pumps, peristaltic pumps, and automated benchtop crossflow systems.

• High Product Yields: The anti-fouling characteristics of the m-PES membrane combined with an unobstructed fluid path prevent premature filter blinding, ensuring high transmission of the target proteins or viruses.

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