Wheaton Spinner Flask 4000 ml Double Sidearm Borosilicate Single Threaded Arm

Wheaton 4000 mL Double Sidearm Spinner Flask – Borosilicate Glass, Mixed Arm Configuration

The Wheaton 4000 mL Spinner Flask is a high-capacity, precision-engineered vessel designed for large-scale cell culture and fermentation. Manufactured from Type I, Class A borosilicate glass, this flask offers exceptional thermal resistance and optical clarity for monitoring delicate cell monolayers or suspension cultures. This specific model features a double sidearm configuration, including one threaded arm and one unthreaded arm, providing a hybrid interface for both airtight sensor integration and traditional venting. Designed for use on a magnetic stir plate, the internal impeller system ensures uniform nutrient distribution and optimal gas exchange, making it a critical tool for scaling up biological production.

Technical Performance and Design

• Borosilicate Glass Construction: Fabricated from low-extractable borosilicate glass that meets USP Type I standards, ensuring chemical purity and the ability to withstand repeated high-temperature autoclave cycles.

• Hybrid Sidearm Interface: Features one threaded sidearm for secure attachment of probes or gas lines and one unthreaded arm for standard venting, offering maximum flexibility for diverse experimental setups.

• Threaded Center Neck: The large center neck is designed to accommodate a threaded headcap and impeller assembly, providing a robust, airtight seal that maintains a sterile environment during long-term incubation.

• Optimal Mixing Dynamics: The flask geometry is engineered to work with Wheaton impeller systems to provide gentle, low-shear agitation, which is essential for protecting sensitive cell lines from mechanical stress.

Product Specifications

• Brand/Manufacturer: Wheaton (DWK Life Sciences)

• Capacity: 4000 mL (4 Liters)

• Material: Borosilicate Glass (USP Type I)

• Sidearm Configuration: Double (1 Threaded / 1 Unthreaded)

• Center Neck Style: Threaded

• Autoclavable: Yes (All components)

• Compatibility: Standard 4L Wheaton impeller and cap assemblies.

Key Benefits & Applications

• Bioprocess Development: Ideal for scaling up from small Erlenmeyer flasks to pilot-scale production for vaccines, recombinant proteins, and monoclonal antibodies.

• Anchorage-Dependent Culture: When used with microcarriers, this flask provides the high surface-to-volume ratio required for the expansion of adherent cells.

• Reduced Contamination Risk: The threaded headcap and sidearm fittings allow for a highly controlled, closed-system environment compared to traditional plug-style flasks.

• Longevity and Reusability: The heavy-wall glass construction is designed for years of service, providing a sustainable and cost-effective alternative to single-use bioreactor bags.

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