Shimadzu Column C18 Nexcol Test Mix 1.8 um 50 x 2.1 mm

The Shimadzu (Part Number 220-91394-03) NexLeaf™ CBX for Potency is a specialized UHPLC column designed specifically for high-throughput analysis, most notably for cannabinoid potency testing. It features a C18 (Octadecylsilane) stationary phase packed with ultra-fine 1.8 µm particles, housed in a compact 50 mm length x 2.1 mm internal diameter stainless steel hardware.

This specific geometry (50 x 2.1 mm, 1.8 µm) is engineered for speed and efficiency. The sub-2-micron particles generate high backpressure but deliver exceptional resolution (theoretical plates), allowing the column to separate structurally similar compounds—such as CBD, THC, and their isomers—in very short run times (often under 8 minutes). The bonded phase is optimized to provide the selectivity needed to resolve critical pairs often found in natural product extracts, ensuring accurate quantitation even in complex matrices.

Because of the small particle size, this column requires a UHPLC system (like the Shimadzu Nexera series) capable of handling higher pressures. It is often sold as the standard column within Shimadzu's "Cannabis Analyzer for Potency" method package.