Agilent Desolvation Assembly for 1100 Series LC/MSD

The Agilent G1946-60336 is a precision-engineered desolvation assembly designed for use with Agilent LC/MS (Liquid Chromatography/Mass Spectrometry) systems. This critical component is part of the atmospheric pressure ionization (API) source interface, specifically developed for the G1946 and early 6100 series Single Quadrupole Mass Spectrometers. The assembly facilitates the efficient removal of solvent from analyte ions before they enter the high-vacuum region of the mass spectrometer, ensuring maximum sensitivity and reducing background noise.

Technical Performance and Design

• Efficient Ion Desolvation: Optimized to provide uniform heat transfer to the mobile phase spray, ensuring complete evaporation of solvents and efficient liberation of gas-phase ions.

• Robust Construction: Manufactured from high-grade stainless steel and temperature-resistant materials to withstand the high thermal loads and chemical exposure typical of LC/MS ion sources.

• Precision Capillary Interface: Designed to house and support the glass or metal capillary that transports ions from the spray chamber into the vacuum manifold.

• Thermal Stability: Engineered to maintain a constant, user-defined temperature, which is essential for reproducible ionization and long-term signal stability.

Product Specifications

• Part Number: G1946-60336

• Component Type: Desolvation / Capillary Support Assembly

• Compatibility: Primarily used with Agilent G1946A/B/C/D and early 6100 series LC/MSD systems.

• Material: Stainless Steel and High-Temperature Insulators

• Connection Type: Integrated heater and sensor electrical connections

• Application: Electrospray Ionization (ESI) and Atmospheric Pressure Chemical Ionization (APCI)

Operational Advantages

• Increased Sensitivity: By improving the efficiency of the desolvation process, this assembly helps deliver a higher density of ions to the detector, lowering limits of detection.

• Reduced Contamination: Proper desolvation prevents un-vaporized solvent droplets from entering the vacuum system, which protects internal ion optics and extends maintenance intervals.

• Direct Compatibility: As an authentic Agilent service part, it ensures a perfect fit and seamless integration with existing source hardware and software controls.

• Serviceability: The modular design allows for straightforward replacement during major source overhauls or when troubleshooting signal loss related to heater or sensor failure.

Removed from a fully operational machine, excellent condition.