Amicon Ultra Centrifuge Filter 15 ml Ultracel 30K Case of 24 Filters

Millipore Amicon Ultra-15 Centrifugal Filter Unit, 30 kDa MWCO, 15 mL Volume (UFC903024) – Case of 24 Units

The Millipore Amicon Ultra-15 Centrifugal Filter Unit (UFC903024) is a high-yield sample preparation device engineered for the rapid concentration, desalinating, buffer exchange, and purification of biological macromolecules. Featuring a 30 kDa Molecular Weight Cut-Off (MWCO) regenerated cellulose Ultracel membrane, this filter unit provides exceptional solute recovery (typically exceeding 90%) while exhibiting extremely low non-specific protein binding. Its vertical membrane design reduces concentration polarization and membrane fouling, enabling fast spin times—typically achieving 50-fold concentration in 10 to 15 minutes. Designed to handle process volumes up to 15 mL in swinging-bucket rotors and 12 mL in 23-degree fixed-angle rotors, the unit incorporates an integrated dead-stop pocket to eliminate the risk of spinning samples to dryness. Supplied as a case of 24 complete filter units with collection tubes, the UFC903024 is ideal for downstream biopharmaceutical processing, antibody purification, nucleic acid isolation, and structural biology applications.

Technical Performance & Structural Attributes

• Ultracel Low-Binding Membrane: High-purity regenerated cellulose matrix delivers superior recovery rates for proteins, antibodies, and large biomolecules greater than 30 kDa.
• Vertical Membrane Alignment: Parallel flow surface minimizes solute buildup and cake formation, maintaining rapid flow rates throughout the centrifugal cycle.
• Built-in Dead-Stop Pocket: Integrated concentrate reservoir prevents sample drying and thermal denaturation, ensuring reliable final concentrate volumes (approx. 200 µL).
• Broad Rotor Adaptability: Fits standard 50 mL conical tube centrifuge rotors, supporting both swinging-bucket and fixed-angle configurations.
• Volumetric Graduations: Transparent polypropylene housing features clear, high-contrast volume markings for real-time monitoring of retentate and filtrate levels.

Product Specifications

• Catalog / Part Number: UFC903024
• Primary Manufacturer: EMD Millipore (MilliporeSigma / Merck KGaA)
• Equipment Category: Laboratory Centrifugal Ultrafiltration Devices
• Membrane Material: Ultracel Low-Binding Regenerated Cellulose
• Nominal Molecular Weight Limit (NMWL) / MWCO: 30 kDa (30,000 Da)
• Maximum Initial Sample Volume: 15.0 mL (Swinging-bucket rotor) / 12.0 mL (Fixed-angle 23-degree rotor)
• Typical Final Concentrate Volume: 150 µL to 300 µL (Dead-stop volume range)
• Maximum Centrifugal Force: 4,000 x g (Swinging-bucket rotor) / 5,000 x g (Fixed-angle 23-degree rotor)
• Housing Components: Polypropylene Filter Body, Polyethylene Cap and Liner, Polypropylene Collection Tube
• Active Membrane Surface Area: 7.6 cm squared
• Dimensions (Diameter x Length): 29.6 mm x 122 mm (Standard 50 mL Tube Form Factor)
• Packaging Configuration: Case of 24 Complete Filter Units with Collection Tubes

Key Benefits & Applications

• Monoclonal Antibody & Enzyme Concentration: Efficiently concentrates high-molecular-weight proteins and IgG antibodies from cell culture supernatants or purification fractions.
• Desalting & Buffer Exchange: Performs rapid diafiltration to remove salts, small molecules, and unbound ligands prior to downstream mass spectrometry or assay analysis.
• Viral & Macromolecular Isolation: Ideal for concentrating viruses, viral vectors, nanoparticle formulations, and large nucleic acid complexes.

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