Corning Culture Flask 75 cm2 Vented Cap Non Treated Case of 100 Flasks

Corning 75 cm2 Cantilever Neck Culture Flasks, Vented Cap, Not Treated, Sterile (431464U) – Case of 100

The Corning 75 cm2 Culture Flasks (431464U) are high-purity, optical-grade biological vessels designed for suspension cell culture, hybridoma propagation, and non-adherent cell line maintenance. Precision-molded from premium virgin polystyrene, these flasks feature an untreated hydrophobic interior surface that prevents unwanted cell adhesion, ensuring high viability and effortless harvesting of suspension cultures. Outfitted with a 0.2 micrometer hydrophobic membrane vented cap, the flasks enable continuous, sterile gas exchange while forming an impenetrable barrier against viral and bacterial contaminants. Supplied as a bulk case of 100 sterile flasks (packaged as 20 inner sleeves containing 5 flasks each), this consumable line delivers certified contamination-free performance for research, clinical, and industrial bioprocessing environments.

Technical Performance & Structural Design

• Non-Treated Hydrophobic Surface: Formulated with a natural, unmodified polystyrene surface that minimizes cell attachment, making it ideal for embryoid body formation, hybridoma growth, and non-adherent cell lines.
• 0.2 µm Hydrophobic Membrane Vented Cap: Integrates a breathable polytetrafluoroethylene (PTFE) membrane inside the cap to allow continuous, sterile air and carbon dioxide exchange while preventing liquid wetting out and microbial penetration.
• Ergonomic Cantilever Neck Profile: Features an angled, wide-mouth neck design that provides unobstructed pipette and cell scraper access to every corner of the growth surface, reducing sample loss during harvesting.
• Optically Clear Crystal Polystyrene: Manufactured to strict distortion-free standards to enable clear, high-contrast microscopic monitoring of suspension cell density and media condition.
• Anti-Tip Stacking Rim: Molded with a raised perimeter rim on the top and bottom surfaces to ensure stable, non-slip stacking inside laboratory incubators.

Product Specifications

• Catalog Number / MPN: 431464U
• Primary Manufacturer: Corning Incorporated
• Growth Surface Area: 75 cm2
• Flask Geometry & Neck Style: Rectangular Body with Cantilever / Angled Neck
• Cap Style Profile: Orange Vented Cap with 0.2 µm Membrane
• Material Composition: Optical-Grade Virgin Polystyrene (PS Body) | High-Density Polyethylene (HDPE Cap)
• Surface Treatment Status: Not Treated (Untreated Hydrophobic Surface)
• Sterility Certification: Pre-Sterilized via Gamma Irradiation (SAL 10-6)
• Purity Profile: Certified non-pyrogenic, non-cytotoxic, and free of detectable RNase and DNase contamination
• Recommended Working Volume: 15 mL to 22.5 mL (Maximum Volumetric Capacity: 250 mL)
• Packaging Configuration: Case of 100 flasks (20 inner sterile sleeves x 5 flasks per sleeve)

Key Benefits & Applications

• Suspension Cell Culture Maintenance: Optimized for growing non-adherent mammalian cell lines, including lymphoblastoid cells, hybridomas, and hematopoietic stem cells.
• Monoclonal Antibody & Recombinant Protein Production: Serves as a reliable, scalable vessel for expanding suspension cells prior to seeding into larger bioreactors or spinner flasks.
• Aseptic Gas Exchange in CO2 Incubators: The membrane cap maintains optimal pH balance without requiring users to loosen caps, reducing the risk of accidental cross-contamination.
• Traceable Cleanroom Packaging: Sub-packaged in small 5-flask sleeves to protect unused inventory from environmental dust when working inside biosafety cabinets.

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