Corning Culture Microplate with Lid 96 Well Treated Polystyrene Case of 50 Plates

Corning 3997 96-Well TC Treated Culture Microplates with Lids (Case of 50)

Engineered for high-throughput cell-based assays and routine mammalian cell culture, the Corning 3997 96-well microplate provides an optimal, standardized platform for complex biological modeling. Precision-molded from highly purified, optically clear virgin polystyrene, these flat-bottom plates offer uncompromised optical clarity for spectrophotometric plate readers and high-resolution phase-contrast microscopy. The internal growth surfaces undergo a proprietary vacuum-gas plasma tissue culture (TC) treatment, generating a uniformly hydrophilic environment that promotes rapid, consistent cellular attachment and monolayer proliferation across all 96 wells. To safeguard critical assays from edge-effects and evaporation, each sterile plate is equipped with a precision-engineered, one-way fitting lid featuring specialized condensation rings. Packaged in a full case of 50 plates, this consumable strictly adheres to standard ANSI/SBS footprint dimensions, ensuring seamless integration with automated liquid handlers, robotic plate washers, and high-content screening systems.

Technical Performance and Design

• Vacuum-Gas Plasma TC Treatment: Permanently alters the hydrophobic polystyrene surface to become hydrophilic, creating an optimal electrochemical environment for the uniform binding of anchorage-dependent cells.

• Optically Clear Flat Bottoms: Delivers superior, distortion-free light transmission that is critical for bottom-reading colorimetric assays, morphological scoring, and continuous visual monitoring of cell confluency.

• Non-Reversible Lids with Condensation Rings: Designed to fit securely in only one orientation to prevent cross-contamination, while integrated rings trap moisture to drastically reduce media evaporation over extended incubation periods.

• Alphanumeric Well Identification: Integrates clearly molded row (A-H) and column (1-12) indexing, accelerating spatial orientation during complex assay setups and significantly reducing the likelihood of pipetting errors.

Product Specifications

• Catalog Number: 3997

• Well Count / Format: 96-Well, Flat Bottom

• Material: Virgin Polystyrene (Tissue Culture Treated)

• Sterility Status: Sterile

• Included Accessories: Non-Reversible Lids

Key Benefits & Applications

• High-Throughput Screening (HTS): The standard 96-well layout and ANSI/SBS footprint accommodate the high-volume processing of compound libraries, maximizing reagent efficiency and laboratory throughput.

• Cell Viability and Toxicity Assays: Provides the optimal well dimensions and optical clarity required for conducting standardized MTT, XTT, or luminescent cell survival screening across multiple experimental conditions.

• Cloning and Viral Titrations: The multi-well format supports the necessary media volumes and spatial separation required for accurate viral plaque enumeration, cloning by limiting dilution, and infectivity studies.

• Workflow Standardization: Uniform surface chemistry across all 96 wells minimizes biological variance and edge-effects, guaranteeing reproducible growth kinetics and reliable data generation across large-scale experiments.

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