Omni International Ceramic Bead Media 2.8 mm Total of 325 grams

Omni International Bulk Ceramic Grinding Bead Media, 2.8 mm (19-646-3) – 325 Grams

The Omni International 19-646-3 is a premium, high-density lysis matrix consumable engineered for the rapid mechanical disruption of challenging biological substrates. Composed of ultra-pure zirconium oxide ($ZrO_2$) ceramic spheres, these 2.8 mm beads are optimized for use within high-energy bead mill homogenizers, including the Omni Bead Ruptor 4, Bead Ruptor 12, Bead Ruptor 24, and Bead Ruptor Elite platforms. The specific density and spherical geometry of the 2.8 mm ceramic media provide an ideal balance of shear and impact forces, fracturing resilient fibrous tissues without causing excessive thermal degradation to sensitive analytes. Supplied as a **325-gram bulk bottle**, this pack enables laboratory facilities to custom-load empty containers—such as **Omni 2 mL Tough Tubes (19-648)**—at a highly economical operational price point.

Technical Performance & Kinetic Mechanics

• High-Density Zirconium Oxide Core: Formulated from advanced zirconium oxide stabilized with yttria, yielding a high material density ($\approx 6.0\text{ g/cm}^3$). This mass delivers superior kinetic energy transfer during multi-directional shaking loops compared to standard glass or silica beads.
• Engineered Shearing Matrix: The 2.8 mm sizing is physically optimized to interface with mid-to-large structural sample boundaries. It is highly effective at tearing through tough animal organs, plant matter, and dense bioprocessing pellets while leaving downstream nucleic acids (DNA/RNA) and proteins intact.
• Chemical and Thermal Inertness: Highly resistant to cracking, chipping, or shattering under violent acceleration speeds (up to 8 m/s). The ceramic composition is completely non-reactive with strong lysis buffers, organic solvents, or acids, preventing heavy-metal contamination or unwanted sample adsorption.
• Bulk Packaging Flexibility: Packaged in a wide-mouth, secure polymer bottle containing 325 grams of dry media. This enables laboratory technicians to alter bead volumes per tube dynamically to optimize extraction performance for non-standard tissue quantities.

Product Specifications

• Catalog Number / MPN: 19-646-3 (Bulk Ceramic Matrix)
• Primary Manufacturer: Omni International (A Revvity Company)
• Bead Diameter Scale: 2.8 mm
• Material Chemistry: Premium Zirconium Oxide ($ZrO_2$) Ceramic | High-Durability Finish
• Approximate Density: $6.0\text{ g/cm}^3$ nominal density profile
• Nuclease Content Baseline: Certified RNase-free, DNase-free, and protease-free prior to field loading
• Compatible Hardware Tracks: Omni Bead Ruptor Series (Optimized for standard 2 mL, 7 mL, or 15 mL tube carriages)
• Total Pack Net Weight: 325 Grams
• Packaging Configuration: Standalone wide-mouth bulk storage bottle with an airtight threaded closure cap

Key Benefits & Applications

• Fibrous and Hard Tissue Disruption: The standard choice for homogenizing resilient biological matrices including animal heart tissue, skeletal muscle, whole brain matter, liver biopsies, and tough plant leaves or stems.
• Custom Matrix Development: Allows laboratories to compound custom multi-size bead mixtures (e.g., pairing 2.8 mm ceramic spheres with smaller 0.1 mm glass beads) to simultaneously lyse hard tissues and cellular membranes within a single run.
• Contamination-Free Extraction Sequencing: The single-use disposal pathway of custom-filled tubes avoids the intensive washing, autoclaving, and cross-contamination risks tied to traditional steel rotor-stator generator probes.
• Downstream Assay Compatibility: Rapid processing ensures rapid cellular release, maximizing yield metrics for downstream extraction cascades including automated column filtration, qPCR validation, and next-generation sequencing (NGS).

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