Teledyne RediSep Gold Reversed Phase 80 g HP Silica Chromatography Column Lot of 5 Columns

Teledyne ISCO RediSep Gold C18 Reversed-Phase Flash Chromatography Column, 80 g, HP Silica (69-2203-348) – Pack of 5 Columns

The Teledyne ISCO RediSep Gold C18 Reversed-Phase Flash Chromatography Column (69-2203-348) is a high-performance purification cartridge engineered for automated flash chromatography systems, including the CombiFlash series. Packed with spherical high-purity (HP) silica bonded with monomeric octadecyl (C18) silane chains, this 80 g column features a fine 20–40 µm particle size and 100 Å pore diameter to deliver superior peak resolution, sharp fraction cuts, and elevated loading capacity. The reversed-phase stationary phase allows efficient separation of moderately polar to strongly hydrophobic organic molecules, peptides, natural products, and synthetic intermediates. Encapsulated in a high-pressure machine-packed polypropylene housing with RFID recognition tags, each column automatically communicates media specifications and pressure limits to compatible automated flash instruments. Supplied as a lot of 5 ready-to-use columns, this configuration ensures reliable batch-to-batch reproducibility across critical medicinal chemistry and organic purification workflows.

Technical Performance & Structural Attributes

• Spherical High-Purity Silica Core: Spherical 20–40 µm silica particle matrix provides high surface area ($~500\text{ m}^2/\text{g}$) and uniform packing density, reducing band broadening compared to irregular silica.
• High-Density C18 Surface Bonding: Monomeric octadecyl (C18) derivatization delivers reproducible hydrophobic retention characteristics across aqueous-organic mobile phases (e.g., Water/Methanol, Water/Acetonitrile).
• Integrated RFID System Communication: Built-in RFID chip stores media type, column size, lot number, and maximum flow/pressure parameters for automated method configuration on CombiFlash systems.
• Engineered High-Pressure Polypropylene Body: Precision molded cartridge shell withstands operating pressures up to 200 PSI (13.8 bar) without leaking or structural deformation.
• Enhanced Loading & Resolution Capabilities: Higher separation efficiency enables twice the sample loading capacity of standard flash columns, dramatically reducing solvent consumption and run times.

Product Specifications

• Catalog / Part Number: 69-2203-348
• Primary Manufacturer: Teledyne ISCO
• Column Family: RediSep Gold C18 Reversed-Phase
• Media Weight / Size: 80 g
• Stationary Phase: Octadecyl (C18) Bonded Silica (Endcapped)
• Particle Shape & Size: Spherical, 20–40 µm
• Pore Size Rating: 100 Å
• Maximum Operating Pressure: 200 PSI (13.8 bar)
• Recommended Flow Rate: 60 mL/min
• Housing Material: Medical-Grade Polypropylene
• Packaging Configuration: Lot of 5 Flash Columns

Key Benefits & Applications

• Reversed-Phase Organic Purification: Ideal for isolating water-soluble, highly polar, or strongly ionic synthetic organic compounds that elute near the solvent front on normal-phase silica.
• Medicinal & Natural Products Chemistry: Provides high-resolution separation for complex natural product extracts, small molecule drug candidates, and peptide fragments.
• Automated High-Throughput Flash Systems: Plug-and-play integration with Teledyne ISCO CombiFlash NextGen, EZ Prep, and Rf systems for rapid, unattended method execution.

All product names, logos, and brands are property of their respective owners. Teledyne ISCO, RediSep, RediSep Gold, and CombiFlash are registered trademarks of Teledyne Instruments, Inc.