Whatman Polycap 75 TC Capsule Filter 0.8/0.2 um with Filling Bell

Whatman Polycap 75 TC Encapsulated Capsule Filter, 0.8/0.2 µm Polyethersulfone Membrane with Filling Bell (6715-7582)

The Whatman Polycap 75 TC Capsule Filter (6715-7582) is a high-capacity, sterile bioprocess capsule filter engineered for the clarification and final sterilizing-grade filtration of biological fluids, cell culture media, buffers, and aqueous solutions. Featuring a dual-layer polyethersulfone (PES) membrane—a 0.8 µm prefilter layer permanently fused over a 0.2 µm final rated membrane—this capsule maximizes total throughput and dirt-holding capacity while protecting the final sterilizing layer from premature fouling. The naturally hydrophilic PES membrane is intrinsically low in protein binding and extractables, ensuring critical biomolecules remain intact during filtration. Encapsulated in a thermally welded, filler-free polypropylene housing, the unit is fitted with a removable filling bell on the outlet nozzle to prevent atmospheric contamination and splashing during sterile bottle-filling operations.

Technical Performance & Structural Attributes

• Asymmetric Dual-Layer PES Membrane: Combines a 0.8 µm depth prefilter layer and a 0.2 µm sterilizing membrane to maximize fluid throughput and extend filter life in viscous or particulate-laden solutions.
• Extremely Low Protein Binding: Polyethersulfone membrane chemistry ensures minimal loss of valuable proteins, enzymes, growth factors, and active pharmaceutical ingredients.
• Integrated Filling Bell Outlet: Includes a protective splash-guard filling bell on the downstream nozzle to ensure sterile, splash-free dispensing into open media bottles and carboys.
• Thermally Welded Polypropylene Housing: Self-contained polypropylene shell eliminates glues, resins, and adhesives, minimizing chemical extractables and leachables.
• Vented Capsule Design: Features an integrated high-point vent to clear trapped air and maximize active filtration membrane surface area during startup.

Product Specifications

• Catalog / Part Number: 6715-7582
• Primary Manufacturer: Whatman (Cytiva / GE Healthcare)
• Equipment Category: Encapsulated Bioprocess Capsule Filter with Filling Bell
• Membrane Material: Dual-Layer Polyethersulfone (PES)
• Housing & Core Material: Polypropylene (PP)
• Pore Size Rating: 0.8 µm Prefilter / 0.2 µm Final Sterilizing Grade
• Effective Filtration Area: 750 cm squared (116 sq. in.)
• Inlet Connection: 1/4 in. to 3/8 in. (6 mm to 10 mm) Stepped Hose Barb
• Outlet Connection: Stepped Hose Barb with Removable Protective Filling Bell
• Maximum Operating Pressure: 4.1 bar (60 psi) at ambient room temperature
• Biosafety & Regulatory Compliance: Pass Class VI USP Plastics testing; non-pyrogenic
• Sterilization & Thermal Limits: Autoclavable at 121 degrees C for 20 minutes

Key Benefits & Applications

• Sterile Cell Culture Media Preparation: Efficiently filters serum-supplemented media, nutrient broths, and salt solutions without absorbing protein additives.
• Downstream Bioprocessing & Buffer Filtration: Clarifies micro-filtered buffers, chromatography reagents, and purified protein fractions prior to column loading.
• Aseptic Bottle Filling: Included filling bell protects open bottle necks from airborne contaminant exposure during sterile bulk transfer in cleanrooms or laminar flow hoods.

All product names, logos, and brands are property of their respective owners. Whatman, Cytiva, and Polycap are registered trademarks of Cytiva / Global Life Sciences Solutions USA LLC.